Depression in patients with acute myocardial infarction: Influence on autonomic nervous system and prognostic role. Results of a five-year follow-up study

Abstract

Word count: 2754 2 ABSTRACT:Background -Although previous studies demonstrated an association between depressive

AAFP Guideline for the Detection and Management of Post-Myocardial Infarction Depression

“…Studies of similar methodological quality published since the EPC report have shown relations between post-MI depression symptoms and hospital readmission 21,26,29 and nonfatal cardiac events or symptoms. 8,13 Two adequately powered studies 26,29 did not support the relation between depression and nonfatal events.…”

Post-myocardial infarction depression: Increased hospital admissions and reduced adoption of secondary prevention measures — A longitudinal study

“…In our cohort, patients with more symptoms of depression were more likely to lack a steady partner than those with fewer symptoms. Other potential mechanisms suggest a direct role for depression in cardiovascular outcomes via cardiac autonomic dysfunction [40], heart rate variability [41] and inflammatory markers [42].…”

High impact of depression in heart failure: Early diagnosis and treatment options

“…Affective disorder patients were reported to show rhythm disturbances with lower HRV values [40][41][42], HRValso being mediated by serotonergic receptors [43]. Controlled studies of comorbidity with ischemic heart disease (IHD) revealed reduced HRVand SDNN [44][45][46] in depressed versus non-depressed individuals. It has been Table 1 Proposed risk factors for developing depression in CHF…”