Depression in Older Age Is a Risk Factor for First Ischemic Cardiac Events

Bremmer, Marijke A.; Hoogendijk, Witte J.G.; Deeg, Dorly J. H.; Schoevers, Robert A.; Schalk, Bianca; Beekman, Aartjan T.F.

doi:10.1097/01.jgp.0000216172.31735.d5

Cited by 69 publications

(45 citation statements)

References 30 publications

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“…Previous articles on LASA, however, have confirmed good validity and high accuracy of our interview and algorithms used to classify the presence or absence of disease states. 17,26 Nonetheless, many patients have asymptomatic atrial fibrillation in later life, which may have underestimated our prevalence of cardiac arrhythmias. 37 Third, the number of participants with a stroke within subgroups was rather low, especially in the subgroup of nondepressed, noncardiac patients.…”

Section: Resultsmentioning

confidence: 99%

“…As previously described 4 : "Cardiac disease was defined as myocardial infarction, congestive heart failure, angina pectoris, or cardiac arrhythmia and established at baseline using an algorithm used earlier in LASA. 26 This algorithm uses 3 sources of information: self-reported, medication, and GP information. We considered only 1 confirmative source necessary for diagnosis because self-reported cardiac disease is sufficiently accurate in LASA (concordance with GP: k 5 0.69; 95% CI 0.65-0.73)."…”

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confidence: 99%

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Depression in context of low neuroticism is a risk factor for stroke

Marijnissen¹,

Wouts²,

Schoevers³

et al. 2014

Neurology

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Objective: Depression predicts stroke; however, meta-analyses show significant heterogeneity.We hypothesize that the risk of depression on incident stroke is conditional upon the relative contribution of vascular disease and of neuroticism in the underlying pathways to depression in a specific patient. We examined whether depression increases stroke in persons with low neuroticism and without preexisting cardiac disease.Methods: This was a population-based cohort study with 9-year follow-up (n 5 2,050; $55 years, 52% female). The incidence of stroke was determined by self-report data as well as data from general practitioners and death certificates. Neuroticism was measured using the Dutch Personality Questionnaire and depression using the Center for Epidemiologic Studies-Depression scale. All data were analysed by Cox proportional hazards regression.

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Section: Resultsmentioning

confidence: 99%

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confidence: 99%

Depression in context of low neuroticism is a risk factor for stroke

Marijnissen¹,

Wouts²,

Schoevers³

et al. 2014

Neurology

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“…26 There is evidence that patients with chronic respiratory and cardiovascular diseases present with higher prevalence of depression, but many studies have not adjusted the association by possible confounders. [27][28] Issa BA et al done a study to know the depression comorbidity among 65 tuberculosis patients with the help of Patient Health Questionnaire (PHQ-9). They concluded that Eighteen (27.7%) of the total patients had depression, comprising 14 (21.5%) with mild depression and four (6.2%) with moderate depression.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of Depression Among Newly Diagnosed MDR Tuberculosis Patients at the Time of Registration- An Experience From Dots Plus Centre

Singh¹,

Verma²,

Kumar³

et al. 2018

jemds

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BACKGROUND MDR tuberculosis remains a leading chronic infection of lung and responsible for significant morbidity and mortality throughout the world and in India also. Depression is also a disorder of major public health importance in terms of its prevalence and the suffering, dysfunction, morbidity and economic burden. Depression and MDR tuberculosis co-exists, because of physical changes from the illness trigger the depression resulting in vicious cycle. So, it is very important to establish the prevalence of depression in MDR tuberculosis. To the best of our knowledge, very little is known about depression in MDR tuberculosis patients.The objective of this study is to find out the prevalence of depression among newly diagnosed MDR tuberculosis patients before the start of Category-IV treatments. MATERIALS AND METHODSThis was a cross-sectional study conducted in Department of Respiratory Diseases, GMC, Kannauj (India). A total of 130 MDR-TB patients were included in the study, which were enrolled for treatment in this unit from January 2017 till June 2017 and assessed at the time of registration for depression. Hamilton depression rating scale (HAM-D) was used to assess depression among MDR-TB patients. RESULTSOne hundred and thirty patients with MDR tuberculosis were enrolled during the study period. There were 93 males (71.5%) and 37 (28.4%) females. The mean age of study subject was 29.45 ± 14.49 years with a male-to-female ratio of 2.5: 1. Depression was not found in 6 (4.62%) patients, whereas 124 (95.3%) of the study participants were classified as depressive on the HAM-D scale. 65 patients (50%) had mild depression, 26 patients (20%) had moderate depression and 33 patients (25.3%) were diagnosed with severe depression. CONCLUSIONDepression is a very important negative factor to treatment adherence and it is important to diagnose and treat depression in time to get the desired results of TB treatment. Multi-drug resistant TB (MDR-TB) is defined as M. tuberculosis resistant to isoniazid and rifampicin with or without resistance to other drugs. Data from studies 'Financial or Other Competing Interest': None. Submission 14-11-2017, Peer Review 07-01-2018, Acceptance 12-01-2018, Published 22-01-2018. Corresponding Author: Dr. Vipul Singh, Associate Professor, Department of Psychiatry, Government Medical College, Kannauj, U. P. E-mail: drvipulsingh@yahoo.co.in DOI: 10.14260/jemds/2018 conducted by NIRT (erstwhile TRC) and NTI, have found MDR-TB levels of 1% to 3% in new cases and around 12% in re-treatment cases. 2-3 RNTCP has recently undertaken three community-based state level drug resistance surveillance (DRS) studies in Gujarat, Maharashtra and Andhra Pradesh. These surveys have been conducted as per a common generic protocol based on internationally accepted methodology and have estimated the prevalence of MDR-TB to be about 3% in new cases and 12% -17% in re-treatment cases. 4 Common mental disorders (CMDs) including depression, anxiety disorders and substance use disorders are a huge...

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“…It is associated with increased risk of first CAD event in elderly women [44] and predicts short term functional decline and associated increased mortality in CHF [41]. Despite documentation that approximately 40% of individual with CHF have depressive symptoms or distress, few trial interventions have been attempted, and none has looked at whether treatment can alter the increased morbidity and mortality that have clearly been demonstrated.…”

Section: Chf Symptoms and Functional Abilitymentioning

confidence: 98%

Symptom perception in CHF: (why mind matters)

Skotzko

2007

Heart Fail Rev

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Symptoms utilized in the clinical care of heart failure as markers of disease severity include, dyspnea, insomnia, low energy, fatigue, poor appetite, and diminished memory. This is despite the fact that physiologic variables such as cardiac ejection fraction and oxygen consumption do not accurately predict functional state in individuals with congestive heart failure (CHF). Distress (anxiety and depression) may amplify symptom complaints without associated physiologic aberration. Personality traits and psychiatric illness, such as mood, anxiety, and psychotic illnesses may also alter perception of somatic symptoms that are associated with this chronic illness. The impact of distress and its treatment on functional performance and CHF symptom reporting deserve additional attention. The need to screen for distress in all with serious symptomatic heart failure is certain.

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Depression in Older Age Is a Risk Factor for First Ischemic Cardiac Events

Cited by 69 publications

References 30 publications

Depression in context of low neuroticism is a risk factor for stroke

Depression in context of low neuroticism is a risk factor for stroke

Prevalence of Depression Among Newly Diagnosed MDR Tuberculosis Patients at the Time of Registration- An Experience From Dots Plus Centre

Symptom perception in CHF: (why mind matters)

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