2019
DOI: 10.1111/jan.14111
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Depression as a mediator of quality of life in patients with neuropathic pain: A cross‐sectional study

Abstract: Aims To explore whether pain intensity has an indirect effect on quality of life through mediation of depression in patients with neuropathic pain (NeP). Design An observational, questionnaire‐based, cross‐sectional study. Methods A convenience sample of patients suffering from NeP were enrolled from June 2015 ‐ May 2016. Three questionnaires were used to collect data of pain intensity, Quality of life and depression. Andrew Hayes' PROCESS macro modelling tool for the SPSS software, based on the mediation Boot… Show more

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Cited by 8 publications
(6 citation statements)
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“…The factors previously determined were confirmed, which allows assessing the practical significance of the results, that is, key variables were identified, which, in this case, are the dimensions (Hair et al, 2009). Data analysis showed that items 3, 16, 21, and 26 loaded on two factors: 1 and 4, 3 and 4, 1 and 3, 1 and 2, respectively, reflecting a conceptual approximation and an interaction between theoretical constructs (psychological conditions) and common points, namely between somatic symptoms and anxiety, between social dysfunction and somatic symptoms, between anxiety and social dysfunction and, finally, between depression and anxiety, which is in line with the literature (Lu et al, 2019). We know that they are symptoms or expressions of individuals' mental state that overlap and influence each other, even because their objective and subjective indicators are often similar.…”
Section: Discussionsupporting
confidence: 84%
“…The factors previously determined were confirmed, which allows assessing the practical significance of the results, that is, key variables were identified, which, in this case, are the dimensions (Hair et al, 2009). Data analysis showed that items 3, 16, 21, and 26 loaded on two factors: 1 and 4, 3 and 4, 1 and 3, 1 and 2, respectively, reflecting a conceptual approximation and an interaction between theoretical constructs (psychological conditions) and common points, namely between somatic symptoms and anxiety, between social dysfunction and somatic symptoms, between anxiety and social dysfunction and, finally, between depression and anxiety, which is in line with the literature (Lu et al, 2019). We know that they are symptoms or expressions of individuals' mental state that overlap and influence each other, even because their objective and subjective indicators are often similar.…”
Section: Discussionsupporting
confidence: 84%
“…In our study, social network, loneliness and depressive symptoms partially mediated the association of VI only, HI only and DSI with QoL, with depressive symptoms having the strongest mediation effect. Depressive symptoms similarly have been reported as a mediator between other non‐sensory‐impairment variables and QoL previously 29 . Our results suggest that efforts to improve the QoL of older adults with VI and HI should consider inclusion of interventions that address these psychosocial factors.…”
Section: Discussionsupporting
confidence: 74%
“…Depressive symptoms similarly have been reported as a mediator between other non-sensory-impairment variables and QoL previously. 29 Our results suggest that efforts to improve the QoL of older adults with VI and HI should consider inclusion of interventions that address these psychosocial factors. For older adults with progressive or irreversible VI and HI, regular monitoring and prompt referrals to relevant social services or further assessments of their psychosocial status may be beneficial.…”
Section: Discussionmentioning
confidence: 77%
“…The molecular neurobiology of chronic pain induces depression and anxiety [ 58 ]. Neuropathic pain and its duration positively corelates with the intensity of mood disorders and has a negative association with quality of life, despite the level of pain intensity [ 13 , 59 , 60 ].…”
Section: Discussionmentioning
confidence: 99%