Depression as a Driving Force for Low Time in Therapeutic Range and Dementia in Patients With and Without Atrial Fibrillation

Rizzi, Scott; Knight, Stacey; May, Heidi T; Woller, Scott C.; Stevens, Scott M.; Steinberg, Benjamin A.; Bair, Tami L; Anderson, Jeffrey L.; Muhlestein, Joseph B.; Knowlton, Kirk U.; Bunch, T. Jared

doi:10.1016/j.amjcard.2021.05.021

Cited by 5 publications

(3 citation statements)

References 17 publications

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“…The prevalence of depression in patients with AF has been reported as high as 38 to 42.7% ( 4 , 5 ), which is similar to that in oncology populations ( 6 – 8 ). A number of studies have indicated that depression was closely related to the occurrence and development of AF, which increase the complexity of management and the risk of adverse outcomes in patients with AF ( 9 – 11 ). The AHA scientific statement Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement has clearly stated that interventions to improve psychological health can have a beneficial impact on cardiovascular health ( 12 ).…”

Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation and Depression: A Bibliometric Analysis From 2001 to 2021

Xing

Yan

et al. 2022

Front. Cardiovasc. Med.

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BackgroundThe control of diseases related to atrial fibrillation (AF) may reduce the occurrence of AF, delay progression, and reduce complications, which is beneficial to the prevention and treatment of AF. An increasing number of studies have shown that AF is associated with depression. However, to date, there has not been a bibliometric analysis to examine this field systematically. Our study aimed to visualize the publications to determine the hotspots and frontiers in research on AF and depression and provide guidance and reference for further study.MethodsPublications about AF and depression between 2001 and 2021 were retrieved from the Web of Science Core Collection (WOSCC) database. CiteSpace 5.8. R1, VOSviewer 1.6.16, and Excel 2019 software tools were used to conduct this bibliometric study.ResultsIn total, 159 articles and reviews were analyzed. The number of publications has been increased sharply since 2018. David D. McManus had the largest number of publications. The most prolific country was the USA with 54 publications but the centrality was <0.1. The most prolific institution was Northeastern University. Three clusters were formed based on keywords: The first cluster was composed of atrial fibrillation, depression, anxiety, symptoms, ablation, and quality of life, et al. The second cluster were risk, prevalence, mortality, heart failure, association, et al. While the third cluster included anticoagulation, impact, stroke, management, warfarin, et al. After 2019, stroke and prediction are the keywords with strongest citation bursts.ConclusionResearch on AF and depression is in its infancy. Cooperation and exchanges between countries and institutions must be strengthened in the future. The effect of depression on prevalence and mortality in AF, depression on ablation in AF, and impact of depression on anticoagulation treatment in AF have been the focus of current research. Stroke prevention (including anticoagulant therapy) is the research frontier, which may still be the focus of research in the future.

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Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation and Depression: A Bibliometric Analysis From 2001 to 2021

Xing

Yan

et al. 2022

Front. Cardiovasc. Med.

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“…Of the included studies, 25 and 14 analyzed the prevalence of depression and anxiety in patients with AF, respectively. One study reported the prevalence of AF in patients with depression[ 14 ]. Details were shown in Table 1 .…”

Section: Resultsmentioning

confidence: 99%

Global epidemiology of mental disorder in atrial fibrillation between 1998-2021: A systematic review and meta-analysis

Zhang,

Liu

et al. 2024

World J Psychiatry

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BACKGROUND As the burden of mental disorders among patients with atrial fibrillation (AF) increases, researchers are beginning to pay close attention to the risk and prevalence of these comorbidities. Although studies have independently analyzed the risk of comorbidity with depression and anxiety in patients with AF, no study has systematically focused on the global epidemiology of these two mental disorders. AIM To explore the prevalence of depression and anxiety in patients with AF. METHODS Five databases were searched from their date of establishment until January 2023. Observational studies reporting the comorbidity of AF with depression and anxiety, were included in this study. Basic information, such as the first author/ publication year, study year, study type, and prevalence of depression and anxiety, were extracted. STATA SE 15.1 was used to analyze the data. Subgroup, meta-regression, and sensitivity analyses were performed to estimate study heterogeneity. RESULTS After a thorough search, 26 studies were identified and included in this meta-analysis. The prevalence rates of depression and anxiety in adults with AF were 24.3% and 14.5%, respectively. Among adult males with AF, the prevalence was 11.7% and 8.7%, respectively, whereas in females it was 19.8% and 10.1%, respectively. In older adults with AF, the prevalence rates of depression and anxiety were 40.3% and 33.6%, respectively. The highest regional prevalence of depression and anxiety was observed in European (30.2%) and North American (19.8%) patients with AF. CONCLUSION In this study, we found that the prevalence of depression and anxiety among patients with AF varies with sex, region, and evaluation scales, suggesting the need for psychological interventions for patients with AF in clinical practice.

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“…Approximately 28–38% of AF patients experience significant depressive or anxious symptoms ( 11 , 48 ), and the interrelationships between these symptoms and AF are multidimensional and complex ( 49 ). Those patients taking the anti-coagulant, warfarin, as a method for stroke prevention are also at an increased risk of depressive symptoms and dementia ( 50 ). These high rates of emotional reactivity may be attributed to AF specific fears, consequences, and demanded psychological adjustment ( 51 ).…”

Section: Fear Of Recurrence: Psychological and Behavioral Aspectsmentioning

confidence: 99%

Fear of Recurrence of Atrial Fibrillation: Translating a Cancer Fear Model to the Atrial Fibrillation Patient Experience

et al. 2022

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BackgroundAtrial fibrillation occurs when rapid and disorganized electrical signals cause the atria in the heart to beat irregularly and is associated with an increased risk for stroke. Despite medical advancements, first and second line atrial fibrillation treatments exhibit significant recurrence rates. Because of this, atrial fibrillation patients often experience disease-specific fears that are not routinely assessed and targeted in clinical management. Fear of recurrence models in cancer research and other cardiac-specific fears have paved the way for a patient-centric approach to disease intervention.PurposeClinical assessment focused solely on the taxonomy of anxiety disorders may miss key components unique to the atrial fibrillation patient experience. An anxiety disorder diagnosis in the presence of an arrhythmia could be misleading and ultimately fail to address patient needs. Modeled from the cancer literature, providers may benefit from a broader disease specific conceptualization for AF patients that differs from a general DSM-5 diagnosis.AimsThe objectives of this paper are: (1) to review the medical aspects of atrial fibrillation, (2) to examine the comparability of fear of recurrence concept from cancer literature to the atrial fibrillation patient, and (3) to suggest considerations of these novel concepts in patient care.Future DirectionsIncreased understanding of fear of recurrence among atrial fibrillation patients aims to define and assess fear of recurrence components, determine treatment targets, and ultimately improve patient outcomes.

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Depression as a Driving Force for Low Time in Therapeutic Range and Dementia in Patients With and Without Atrial Fibrillation

Cited by 5 publications

References 17 publications

Atrial Fibrillation and Depression: A Bibliometric Analysis From 2001 to 2021

Atrial Fibrillation and Depression: A Bibliometric Analysis From 2001 to 2021

Global epidemiology of mental disorder in atrial fibrillation between 1998-2021: A systematic review and meta-analysis

Fear of Recurrence of Atrial Fibrillation: Translating a Cancer Fear Model to the Atrial Fibrillation Patient Experience

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