Depression and quality of life in older adults on hemodialysis

Abstract

Objective: Depression is highly prevalent in hemodialysis patients, but few studies have evaluated older hemodialysis patients. The aim of this study was to evaluate the prevalence of depression, its associated factors and its impact on quality of life in an older population on hemodialysis. Methods: This was a cross-sectional study including 173 hemodialysis patients aged 60 years or older in Recife, Brazil. Depression was evaluated using the Mini-International Neuropsychiatric Interview when depressive symptoms (according to the 5-item Geriatric Depression Scale) were present. Quality of life was assessed with the Control, Autonomy, Self-realization and Pleasure Questionnaire (CASP-16). Data were also collected on sociodemographic, laboratory (albumin, parathormone, hemoglobin, and phosphorus) and dialysis (dialysis vintage, vascular access and hemodialysis adequacy) characteristics. Results: Depression was present in 22.5% of the sample. Depressed patients presented low CASP-16 quality of life scores (31.6 vs. 24.2, p o 0.001), twice the odds of albumin levels o 3.8 g/dL (OR 2.36; 95%CI 1.10-5.07; p = 0.027) and higher parathormone levels (OR 1.06; 95%CI 1.00-1.13; p = 0.05). Conclusion: Older hemodialysis patients have a high prevalence of depression. Depressed patients presented poor quality of life, lower serum albumin and higher parathormone levels. Teams dealing with older hemodialysis patients should include depression and quality of life assessments in care protocols.

Influence of Depression and Anxiety on Hemodialysis Patients: The Value of Multidisciplinary Care

“…Serum albumin levels were determined as a risk factor of depression in our multiple regression analysis, a finding which could support two previous studies from Taiwan [ 26 ] and Brazil that confirmed the clinical relevance of [ 27 ] the influence of depression on appetite as a rational for a significantly worse nutritional status in HD patients. In this sense, our results would also reinforce the suggestion of Friend et al to take seriously the association between depression and nutritional status in HD units due to its additive effect on patients’ mortality [ 28 ].…”

Association between Financial Hardship and Symptom Burden in Patients Receiving Maintenance Dialysis: A Systematic Review

“…Among the included studies, seven were conducted in Mainland China [27][28][29][30][31][32][33], and five each were conducted in Brazil [34][35][36][37][38], Turkey [39][40][41][42][43], and the USA [44][45][46][47][48] (Supplementary Material S3). Nine studies were from the Middle East [49][50][51][52][53][54][55][56][57], and seven were from South Asian countries [58][59][60][61][62][63][64].…”

Overlap of Depressive Symptoms with Health-Related Quality-of-Life Measures

“…But the authors concluded that quality of life was more important than depression because it was I have trouble remembering significant in the model that included both independent variables. The authors did not acknowledge the overlap between the variables even though they reported a significant association between them in a separate article [12]. Wang et al [13] analyzed cross-sectional data from a sample of 420 elderly in rural China and found a significant correlation of − 0.32 between depressive symptoms (PHQ) and the World Health Organization Quality of Life Assessment (WHO-QOL-BREF).…”