Depression and hopelessness in patients with acute leukemia: the psychological impact of an acute and life‐threatening disorder

Gheihman, Galina; Zimmermann, Camilla; Deckert, Amy; Fitzgerald, Peter; Mischitelle, Ashley; Rydall, Anne; Schimmer, Aaron D.; Gagliese, Lucia; Lo, Chris; Rodin, Gary

doi:10.1002/pon.3940

Cited by 49 publications

(46 citation statements)

References 40 publications

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“…Hopelessness implies negative expectations about the future, pessimism, lack of enthusiasm and loss of meaning, and predicts suicidal ideation better than depression . Few studies have investigated the psychological impact of disabling medical conditions and the correlates of depression and hopelessness, and those that have mainly involved patients suffering from oncological and cardiac diseases . While hopelessness correlated with perceived disability in PD, no such correlation was detected between hopelessness and suicide association.…”

Section: Discussionmentioning

confidence: 99%

“…43 Few studies have investigated the psychological impact of disabling medical conditions and the correlates of depression and hopelessness, and those that have mainly involved patients suffering from oncological and cardiac diseases. [44][45][46][47] While hopelessness correlated with perceived disability in PD, no such correlation was detected between hopelessness and suicide association. This is an unexpected result that confirms that suicidal ideation in PD is more closely linked to the perception of disability than to other psychopathological variables.…”

Section: Discussionmentioning

confidence: 99%

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Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

et al. 2018

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Summary Background Previous studies investigating the risk of suicide in patients with Parkinson's disease (PD) have reported conflicting results. This study evaluated suicide risk in PD and investigated the relationship between suicide risk and perceived disability, hopelessness and affective temperaments in PD. Methods One‐hundred and twenty PD patients were consecutively enrolled. The diagnosis of PD was based on clinical criteria. All patients underwent a psychiatric evaluation that included the administration of the Columbia‐Suicide Severity Rating Scale, the Italian Perceived Disability Scale, the Beck Hopelessness Inventory and the TEMPS‐A questionnaire. The results were compared with those of a control group of 91 patients affected by another chronic disease, ie, open angle glaucoma. Results Parkinson's disease patients had higher suicidal ideation, higher perceived disability and lower hyperthymia than the control group. In PD, higher perceived disability was associated with higher current and lifetime suicidal ideation, lower hyperthymia, older age and higher scores on negative temperaments. Suicidal ideation, negative temperaments and hopelessness were risk factors for perceived disability, while hyperthymia was a protective factor for perceived disability. Discussion Patients with PD have an increased risk of suicidal ideation. Increased suicidal ideation in PD is associated with the increased perceived disability. A psychiatric assessment that includes the investigation of suicide risk and perceived disability is recommended in patients with PD.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

et al. 2018

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“…Data suggest that patients with hematologic malignancies face significant challenges regarding emotional well-being, which in some cases may be more significant than that faced by patients with many solid tumor types. [27–29] Here too, differences in setting of care may explain this finding, yet if anything it remains the case that hematology patients probably need more attention to emotional well-being issues than they are currently receiving. Challenges related to the assessment and management of symptoms and emotional needs should be the focus of ongoing research and intervention development in hematologic malignancies.…”

Section: Discussionmentioning

confidence: 99%

Adherence to Measuring What Matters Items When Caring for Patients With Hematologic Malignancies Versus Solid Tumors

LeBlanc

Ritchie

Friedman

et al. 2016

Journal of Pain and Symptom Management

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Context “Measuring What Matters” (MWM) prioritizes quality measures in palliative care practice. Hematologic malignancy patients are less likely to access palliative care, yet little is known about their unique needs. Differences in MWM adherence may highlight opportunities to improve palliative care in hematology. Objectives To assess adherence to MWM measures by palliative care clinicians caring for patients with hematologic malignancies, compared to those with solid tumors. Methods We used the Quality Data Collection Tool (QDACT) to assess completion of MWM measures across nine sites. Results We included data from 678 patients’ first visits and various care settings; 64 (9.4%) had a hematologic malignancy, while 614 (90.6%) had a solid tumor. Hematology patients were more likely to be seen in a hospital (52 or 81.3% vs. 420 or 68%), while solid tumor patients were more frequently seen at home or in clinics (160 (26%) vs. 7 (10.9%)). Of the 9 MWM measures we assessed, high adherence (>90%) was seen regardless of tumor type in measures #3 (Pain Treatment), #7 (Spiritual Concerns), #8 (Treatment Preferences) and #9 (Care Consistent with Preferences). Clinicians seeing hematology patients were significantly less likely to meet measures #2 (Screening for Physical Symptoms; 57.8% vs 84.2%, p<0.001), and #5 (Discussion of Emotional Needs; 56.3 vs 70.0%, p=0.03). Conclusion MWM adherence regarding symptom assessment and meeting emotional needs was lower for patients with hematologic malignancies compared to those with solid tumors. This finding suggests two key areas for quality improvement initiatives in palliative care for patients with hematologic malignancies.

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“…Both an insecure attachment style and impaired communication with HCPs can have important clinical consequences, such as depression, impaired treatment compliance, and demoralization. 7,21,46 However, further research is needed to demonstrate the clinical significance of our findings on the interaction of these variables.…”

Section: Cares-mis = Cancer Rehabilitationmentioning

confidence: 88%

“…The systemic and complex nature of AL also makes it difficult for patients to understand their condition and treatment. These factors may contribute to significant depression and traumatic stress in this population, both of which have been associated with difficulties with communication . Relapse in AL may be associated with even greater distress and mortality, and heightened communication needs …”

Section: Introductionmentioning

confidence: 99%

The experience of medical communication in adults with acute leukemia: Impact of age and attachment security

et al. 2018

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Background Health care providers' (HCPs) communication with cancer patients provides both information and support. Younger patient age and greater difficulty accepting support (attachment security) have been linked to poorer communication experiences with HCPs. The present secondary data analysis examined the impact of age group and attachment security on perceived communication problems with HCPs in adults with acute leukemia (AL). Methods The sample included 95 younger (age < 40 years) and 225 older (age ≥ 40 years) patients with newly diagnosed or recently relapsed AL. We assessed avoidant and anxious attachment security (reluctance to accept support and fear of its unavailability, respectively) with the modified 16‐item Experiences in Close Relationships Scale. The impact of age group and attachment security on perceived communication problems, measured with the Cancer Rehabilitation Evaluation System‐Medical Interaction Subscale, was assessed based on the presence and extent of communication problems. Results Younger patients (OR = 1.79‐1.82, P = .030) and those with greater avoidant (OR = 1.44, P = .001) or anxious attachment (OR = 1.38, P = .009) were more likely to report communication problems. A similar relationship was found between age (β's = −.17‐.19, P = .015‐.025), avoidant (β = .29, P = .013), or anxious attachment (β = .17, P = .031), and the extent of communication problems. A significant age‐group × avoidant‐attachment interaction (β = −.31, P = .008) suggested that more avoidant attachment was associated with more perceived communication problems in the younger but not in the older group. Conclusions Younger patients with AL, especially those more reluctant to seek or accept support, perceive more communication problems with their HCPs than older patients. Greater attention by HCPs to their communication with younger patients is needed.

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Depression and hopelessness in patients with acute leukemia: the psychological impact of an acute and life‐threatening disorder

Cited by 49 publications

References 40 publications

Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

Suicidal ideation, perceived disability, hopelessness and affective temperaments in patients affected by Parkinson's disease

Adherence to Measuring What Matters Items When Caring for Patients With Hematologic Malignancies Versus Solid Tumors

The experience of medical communication in adults with acute leukemia: Impact of age and attachment security

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