2017
DOI: 10.2147/cia.s113576
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Depression and chronic pain in the elderly: links and management challenges

Abstract: Aging is an inevitable process and represents the accumulation of bodily alterations over time. Depression and chronic pain are highly prevalent in elderly populations. It is estimated that 13% of the elderly population will suffer simultaneously from the two conditions. Accumulating evidence suggests than neuroinflammation plays a critical role in the pathogenesis of both depression and chronic pain. Apart from the common pathophysiological mechanisms, however, the two entities have several clinical links. Th… Show more

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Cited by 288 publications
(242 citation statements)
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References 140 publications
(137 reference statements)
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“…As in all conditions causing chronic pain, CTS has a negative effect on mental health in patients (Zis et al, ). The presence of chronic pain in CTS may play a large role in the mental health difficulties seen in CTS patients.…”
Section: Introductionmentioning
confidence: 99%
“…As in all conditions causing chronic pain, CTS has a negative effect on mental health in patients (Zis et al, ). The presence of chronic pain in CTS may play a large role in the mental health difficulties seen in CTS patients.…”
Section: Introductionmentioning
confidence: 99%
“…Lu et al found that when compared with American participants, Chinese participants in Hong Kong are more likely to report somatic symptoms instead of depressed feelings. The somatic symptoms include fatigue, pain, loss of appetite, and sleep problems …”
mentioning
confidence: 99%
“…Both pharmacological and alternative therapies should be utilized for this population, especially for individuals with comorbidities [87]. AAs who receive outpatient mental health care incur lower costs for inpatient and emergency medical care [88].…”
Section: Discussionmentioning
confidence: 99%