Depression and Anxiety in Patients With Lichen Sclerosus

Fan, Ryan; Leasure, Audrey C; Maisha, Fahrisa I.; Little, Alicia J.; Cohen, Jeffrey M.

doi:10.1001/jamadermatol.2022.1964

Cited by 9 publications

(6 citation statements)

References 8 publications

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“…Patients often experience anxiety, depression, and stress associated with their disease, which can adversely affect their quality of life and treatment outcome. VLS has been shown to have a signi cant impact on the mental and psychosocial health of women [20,21]. In our study, 61.2% of the patients considered it di cult to manage their fear of cancer.…”

Section: Discussionmentioning

confidence: 63%

Survey analysis of patient satisfaction and sexual issues in the management of vulvar lichen sclerosus

Meyer-Wilmes,

Wittenborn,

Kupec

et al. 2024

Preprint

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Objective Vulvar lichen sclerosus (VLS) is an underestimated chronic disease. It can cause significant symptom burden and sexual dysfunction. This study aimed to evaluate patient satisfaction and current challenges in the management of VLS in a certified dysplasia unit, particularly during the COVID-19 pandemic. Methods This survey analyzed patients who had been diagnosed with VLS and treated at our DKG-certified dysplasia unit. The study was conducted during the COVID-19 pandemic in the Department of Gynecology and Obstetrics at the University of Aachen. The questionnaire contained 43 questions covering general treatment, diagnostic delays, psychological and sexual issues and specific questions about the COVID-19 pandemic. The questionnaire was distributed between January 2021 and September 2023. Results This study included 103 patients diagnosed with VLS who were treated at our certified dysplasia unit. Overall, 48% of the patients were satisfied with the success of the therapy. Most participants reported psychological problems (36.8%), fear of cancer (53.3%), or sexual restrictions (53.3%). Among the patients, 38% were bothered by the regular application of topical cortisone. However, 72% were willing to undergo treatment for more than 24 months. The COVID-19 outbreak in March 2020 had a significant negative impact on general VLS care from the patient’s perspective (3,83/5 before vs. 3,67/5 after; p = 0.046). There was a general request for booklets to inform and educate patients about their disease. Furthermore, the respondents demanded a telephone hotline to answer the questions and wished for follow-up visits via e-mail to cope better with their current situation. Conclusion This study highlights the need for more effective treatments for VLS and an increased awareness of psychological and sexual distress. To ensure patient well-being and satisfaction, it is imperative to offer individualized care in a team of specialists from various disciplines.

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Section: Discussionmentioning

confidence: 63%

Survey analysis of patient satisfaction and sexual issues in the management of vulvar lichen sclerosus

Meyer-Wilmes,

Wittenborn,

Kupec

et al. 2024

Preprint

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“…Women with LS had a 2.16-to-2.5-fold increase or receiving a diagnosis of comorbid depression or anxiety compared with the control group. 32 However, Fiocco et al reported that no significant differences in stress levels were observed between both sexes. 13 Based on the Depression, Anxiety, and Stress Score (DASS-21), most patients experienced moderate to extremely severe depression, anxiety, and stress.…”

Section: Discussionmentioning

confidence: 97%

Depression, Anxiety, Stress, Associated with Lichen Planus in Jordanian Women and the Impact on Their Quality of Life

Alnazly,

Absy,

Sweileh

2023

IJWH

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To identify mental health problems in patients with lichen planus (LP). We evaluated the impact of LP on patients' mental health and quality of life and the associations with sociodemographic and clinical characteristics. Materials and Methods: This cross-sectional study was conducted in Amman, Jordan, between August 2022 and May 2023. We conducted a survey of 126 women with LP mean age of 48.61 years and a standard deviation of 15.25 years. The survey included sociodemographic characteristics, the Arabic version of the Dermatology Life Quality Index (DLQI), and the 21-item Depression, Anxiety, and Stress scale. Results: The DLQI scores indicated that LP had substantial effects on the quality of life of most of the participants (63.5%), and the condition was significantly correlated with depression (r = 0.381), anxiety (r = 0.469), and stress (r = 0.475). Longer disease duration and misdiagnosis prior to LP diagnosis were also significantly correlated with quality of life (r = 0.388 and r = 0.317, respectively), as were the LP symptoms. The most robust correlation coefficients were observed for itching symptoms and location in the genital area (r = 0.277 and r = 0.354), respectively. Conclusion: Depression, anxiety, and stress can significantly reduce the quality of life among patients with LP. This study proves the need for healthcare providers to consider interventions that improve the psychological well-being and QOL of patients. Additionally, this study highlights the importance of the implementation of evidence-based practice to improve the timely diagnosis of LP. It is essential to follow a comprehensive approach when diagnosing and treating LP. This involves a multidisciplinary collaboration between different specialties as well focusing on patient education.

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“…Patients often experience anxiety, depression, and stress associated with their disease, which can adversely affect their quality of life and treatment outcome. VLS has been shown to have a significant impact on the mental and psychosocial health of women [ 21 , 22 ]. In our study, 61.2% of patients considered it difficult to manage their fear of cancer.…”

Section: Discussionmentioning

confidence: 99%

Patient satisfaction and sexual issues in vulvar lichen sclerosus treatment: a monocentric certified dysplasia unit survey analysis

Meyer-Wilmes,

Wittenborn,

Kupec

et al. 2024

Arch Gynecol Obstet

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Objective Vulvar lichen sclerosus (VLS) is an underestimated chronic disease. It can cause significant symptom burden and sexual dysfunction. This study aimed to evaluate patient satisfaction and current challenges in the management of VLS in a certified dysplasia unit, particularly during the COVID-19 pandemic. Methods This survey analyzed patients who had been diagnosed with VLS and treated at our DKG-certified dysplasia unit. The study was conducted during the COVID-19 pandemic in the Department of Gynecology and Obstetrics at the University of Aachen. The questionnaire contained 43 questions on general treatment, diagnostic delays, disease education, psychologic and sexual issues, and specific questions regarding the COVID-19 pandemic. The questionnaires were distributed between January 2021 and September 2023. Results This study included 103 patients diagnosed with VLS, who were treated at our certified dysplasia unit. Overall, 48% of the patients were satisfied with the success of the therapy. Most participants reported psychologic problems (36.8%), fear of cancer (53.3%), or sexual restrictions (53.3%). Among the patients, 38% were bothered by the regular application of topical cortisone. However, 72% were willing to undergo treatment for more than 24 months. The COVID-19 outbreak in March 2020 had a significant negative impact on general VLS care from the patient’s perspective (3.83/5 before vs. 3.67/5 after; p = 0.046). There was a general request for booklets to inform and educate the patients about their disease. Furthermore, the respondents demanded a telephone hotline to answer the questions and wished for follow-up visits via e-mail to cope better with their current situation. Conclusion This study highlights the need for more effective treatments for VLS and an increased awareness of psychologic and sexual distress. To ensure patient well-being and satisfaction, it is imperative to offer individualized care with adequate disease education in a team of specialists from various disciplines.

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Depression and Anxiety in Patients With Lichen Sclerosus

Abstract: This case-control study uses data from the National Institutes of Health All of Us Research Program to investigate whether depression and anxiety are associated with lichen sclerosus among women.

Cited by 9 publications

References 8 publications

Survey analysis of patient satisfaction and sexual issues in the management of vulvar lichen sclerosus

Survey analysis of patient satisfaction and sexual issues in the management of vulvar lichen sclerosus

Depression, Anxiety, Stress, Associated with Lichen Planus in Jordanian Women and the Impact on Their Quality of Life

Patient satisfaction and sexual issues in vulvar lichen sclerosus treatment: a monocentric certified dysplasia unit survey analysis

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