Depot grass-pollen injections in asthma: effect of repeated treatment on clinical response and measured bronchial sensitivity.

McAllen, Monica K.; Heaf, P. J. D.; McInroy, P.

doi:10.1136/bmj.1.5531.22

Cited by 25 publications

(3 citation statements)

References 4 publications

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“…A further 125 studies were excluded from this review (77–201). The most common but not mutually exclusive reasons for exclusion were as follows: 37 studies were not randomized (84, 86, 91, 93, 97, 98, 103, 105, 108, 114, 116, 120, 122, 123, 126, 130, 132, 133, 135, 140, 145, 146, 149, 151, 157, 159, 163, 164, 166, 176, 177, 180, 185, 189, 193, 194, 198), 25 studies were not controlled (87–89, 99, 101, 107, 115, 121, 128, 131, 134, 137, 140, 148–150, 155, 169, 172, 181, 184, 189, 195, 199, 201), 29 studies solely or predominantly involved subjects who had allergic rhinitis/conjunctivitis rather than asthma (77, 79, 80, 82, 85, 90, 94, 96, 100, 108–113, 117–…”

Section: Resultsmentioning

confidence: 99%

Immunotherapy in asthma: an updated systematic review

Abramson

Puy

Weiner

1999

Allergy

147

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Section: Resultsmentioning

confidence: 99%

Immunotherapy in asthma: an updated systematic review

Abramson

Puy

Weiner

1999

Allergy

147

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“…These patients had quantitative skin tests with the corresponding antigens, and four of them (Cases 3, 4, 6, and 11) had a quantitative bronchial tolerance test (McAllen, Heaf, and McInroy, 1967). The other three patients also had extensive investigations, including direct and Prausilitz-Kustner skin tests.…”

Section: Skin Testsmentioning

confidence: 99%

Detection of Allergy to Penicillin and Other Antigens by In-vitro Passive Sensitization and Histamine Release from Human and Monkey Lung

Assem¹,

Schild²

1968

BMJ

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ummary: Preparations of chopped human and monkey lung were used to estimate the reaginic activity of serum from allergic patients. The lung preparation was passively sensitized by incubation with serum taken from the patients, and then challenged with the antigen responsible for the allergy. Measurement of the histamine released from the lung gave a quantitative assessment of the level of reaginic activity in the patient's serum.Tests were done on patients allergic to four natural antigens, including grass pollen, and to penicillin. Human lung proved more sensitive and possibly more specific than monkey lung in testing for natural allergies. The results of testing for penicillin allergies were less satisfactory, possibly because of the difficulty of reconstructing the appropriate antigen.

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“…Apart from its value in studies of chronic bronchitis in relation to air pollution, it has been used to study variations of the severity of rheumatoid arthritis with changes in weather. A similar approach has also been used to assess the results of treatment among asthmatic patients (McAllen, Heaf, and Mclnroy, 1967;British Tuberculosis Association, 1968). As it is essential to maintain the patients' interest and co-operation, efforts have been made to find out which method of recording (on printed sheets, postcards, or pocket diaries) the patients preferred.…”

Section: Discussionmentioning

confidence: 99%