Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cristescu, R.; Popescu, C.; Socol, G.; Visan, Anita Ioana; Mihăilescu, I. N.; Gittard, Shaun D.; Miller, Philip R.; Martin, Timothy N; Narayan, Roger J.; Andronie, A.; Stamatin, I.; Chrisey, Douglas B.

doi:10.1016/j.apsusc.2010.11.141

Cited by 33 publications

(17 citation statements)

References 51 publications

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“…For example, Bubb et al showed that polyethylene glycol coatings deposited using MAPLE exhibited the same chemical structure as the starting material [48]. In subsequent work, Cristescu et al created films containing poly(1,3-bis-(p-carboxyphenoxy propane)-co-sebacic anhydride) and gentamicin using MAPLE [49]. In vitro studies confirmed the activity of the gentamicin-doped films against E. coli and Staphylococcus aureus.…”

Section: Laser Processing Of Biomaterialsmentioning

confidence: 79%

Laser Engineering of Surface Structures

Narayan

Goering

Balani³

et al. 2014

Biosurfaces

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Over the past half century, rapid progress has been made in laser-based medical diagnosis and treatment, as well as in laser-based medical device fabrication. Lasers have unique capabilities for coating, machining, melting, polymerizing, sintering, and welding materials that are used in implantable and transdermal medical devices. In this review, academic and industrial developments involving laser processing of materials for dental, orthopedic, neural, ophthalmic, cardiovascular and transdermal applications are described. In addition, laser processing of nanoscale materials for medical applications is discussed. Finally, the challenges associated with commercialization of laser biomaterials are considered. Due to the unique capabilities provided by laser-based processes, it is anticipated that the use of laser biomaterials in implantable and transdermal medical devices will markedly increase over the coming years.

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Section: Laser Processing Of Biomaterialsmentioning

confidence: 79%

Laser Engineering of Surface Structures

Narayan

Goering

Balani³

et al. 2014

Biosurfaces

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“…In our previous work, we used the MAPLE technique as a new approach for the deposition of coatings containing gentamicin [24,25] embedded polymeric matrices or silver nanoparticles for antimicrobial applications [26]. In view of obtaining improved coatings capable of modulating and controlling microbial biofilm behavior, we used MAPLE to fabricate thin films resistant to microbial colonization, containing natural (quercetin flavonoid) and synthetic (norfloxacin and cefuroxime antibiotics) compounds.…”

Section: Introductionmentioning

confidence: 99%

Successful Release of Voriconazole and Flavonoids from MAPLE Deposited Bioactive Surfaces

et al. 2019

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We explored the potential of biomimetic thin films fabricated by means of matrix-assisted pulsed laser evaporation (MAPLE) for releasing combinations of active substances represented by flavonoids (quercetin dihydrate and resveratrol) and antifungal compounds (amphotericin B and voriconazole) embedded in a polyvinylpyrrolidone biopolymer; the antifungal activity of the film components was evaluated using in vitro microbiological assays. Thin films were deposited using a pulsed KrF* excimer laser source which were structurally characterized using atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR). High-quality thin films with chemical structures similar to dropcast ones were created using an optimum laser fluence of ~80 mJ/cm2. Bioactive substances were included within the polymer thin films using the MAPLE technique. The results of the in vitro microbiology assay, which utilized a modified disk diffusion approach and were performed using two fungal strains (Candida albicans American Type Culture Collection (ATCC) 90028 and Candida parapsilosis American Type Culture Collection (ATCC) 22019), revealed that voriconazole was released in an active form from the polyvinylpyrrolidone matrix. The results of this study show that the MAPLE-deposited bioactive thin films have a promising potential for use in designing combination devices, such as drug delivery devices, and medical device surfaces with antifungal activity.

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“…Gentamicin sulfate, a antibiotic against Staphylococcus aureus, Escherichia coli, and many other bacteria. The co-polymer which mixed by this antbiotic was deposited by MAPLE [41]. This anit-microbial polymer films are used for prevent the infaction caused by the bacteria from implants and catheters.…”

Section: Recent Progress Of Maple Biomaterialsmentioning

confidence: 99%

Matrix-Assisted Pulsed Laser Evaporation (MAPLE) technique for deposition of hybrid nanostructures

Yang¹,

Zhang²

2017

Front Nanosci Nanotech

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This review paper provides the detailed information on a new nano-manufacturing process for producing nanocomposites, i.e., the matrix-assisted pulsed laser evaporation (MAPLE). Owing to its unique advantages in depositing polymers and biomaterials, MAPLE technique has been applied to fabricate coatings for medical implants, and electronic devices. In this paper, the current progress on the applications of MAPLE technique is reviewed and discussed. MAPLE techniques have demonstrated a precise control of the parameter such as film thickness and roughness, material structure after deposition. The potentials of MAPLE technique in nanobiotechnology are also discussed in this review paper.

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Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cited by 33 publications

References 51 publications

Laser Engineering of Surface Structures

Laser Engineering of Surface Structures

Successful Release of Voriconazole and Flavonoids from MAPLE Deposited Bioactive Surfaces

Matrix-Assisted Pulsed Laser Evaporation (MAPLE) technique for deposition of hybrid nanostructures

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