Deployment of the French Military Field Laboratory Dedicated to Ebola Virus Infected Patients in Guinea, January–July 2015

Janvier, Frédéric; Foissaud, Vincent; Delaune, D.; Flusin, Olivier; Dubrous, P.; Nab, Christine Mac; Gaillard, Tiphaine; Perez, Pascale; Poyot, Thomas; Paucod, Jean-Charles; Richard, Stéphane; Ferraris, Olivier; Delacour, Hervé; Bigaillon, C.; Leparc-Goffard, I; Peyrefitte, Christophe N.; Brisou, P.; Renard, Christophe; Garnotel, Éric; Koeck, Jean-Louis; Thibault, François M.; Valade, Eric; Mérens, Audrey

doi:10.1093/infdis/jiv554

Cited by 8 publications

(3 citation statements)

References 4 publications

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“…In this exceptional home mission of the French Army Health Service, the EMRSSA's health rules, design and logistics were based on the operational experience of the Service, especially during the deployment of a field laboratory in Guinea in 2015 in the fight against the Ebola virus [17]. The EMRSSA was structured in 3 distinct hygiene zones (Fig.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous dilatational tracheostomy for saturating influx of COVID-19 patients: Experience of military ENT physicians deployed in Mulhouse, France

Morvan

Rivière

Déserts

et al. 2020

European Annals of Otorhinolaryngology, Head and Neck Diseases

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Objectives: The main objective was to demonstrate the feasibility of percutaneous tracheostomy performed under difficult conditions by military ENT physicians during their deployment in the military intensive care field hospital of the French Military Medical Service in Mulhouse to confront the exceptional COVID-19 pandemic. The secondary objective was to assess reliability and safety for patient and caregivers, with a risk of iatrogenic viral contamination. Material and methods: A single-center retrospective study was conducted between March 25 and April 25, 2020, in 47 COVID-19 patients requiring prolonged mechanical ventilation. The inclusion criterion was having undergone percutaneous tracheostomy. Results: Eighteen consecutively included patients had successfully undergone percutaneous tracheostomy despite unfavorable anatomical conditions (short neck: 83.3%, overweight or obese: 88.9%). Median time to completion was 11 days after intubation, with an average duration of 7 minutes. The procedure was technically compliant in 83.3% of cases, and considered easy (on self-assessment) in 72.2%, with 2 minor per-procedural complications. No crossover to surgery was required. There was only 1 major post-procedural complication (late hemorrhage). Conclusion: This study showed the feasibility of percutaneous tracheostomy by an ENT physician under COVID-19 biohazard conditions. The technique was fast, easy and safe and met safety requirements for patient and staff.

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Section: Discussionmentioning

confidence: 99%

Percutaneous dilatational tracheostomy for saturating influx of COVID-19 patients: Experience of military ENT physicians deployed in Mulhouse, France

Morvan

Rivière

Déserts

et al. 2020

European Annals of Otorhinolaryngology, Head and Neck Diseases

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“…The objective was to maximize the utility of the interventions while not putting the healthcare workers at increased risk. Laboratory facilities enabled the diagnosis of Ebola virus infection and the measurement of a panel of biological and biochemical parameters [58] . The caregiver treatment centre offered conditions for the care and study of Ebola virus–infected patients never previously available in developing countries or in an epidemic context.…”

Section: Discussionmentioning

confidence: 99%

Contribution of the French army health service in support of expertise and research in infectiology in Africa

Pradines

Rogier²

2018

New Microbes and New Infections

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Historically, infectious diseases have caused more casualties than battle. The French military health service therefore developed a range of research on vector-borne diseases such as malaria and arboviruses, antibiotic resistance, infectious agents that can be used as biological weapons and vaccines. The main objective is to control naturally acquired or provoked infectious diseases and limit their impact on armed forces as well as on civilian populations in France or abroad, particularly in Africa and anywhere French armies may be deployed. The expertise of the military health service teams in manipulating agents requiring high level of biosafety precautions and in organizing and providing medical care in unnatural conditions, including the battlefield, associated with complementarity staff experience (physicians, biologists, epidemiologists, researchers, pharmacists, logisticians), has been used in the management of the Ebola outbreak in Guinea.

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“…Current EVD detection depends on polymerase chain reaction (PCR)-based diagnosis, largely conducted in centralised laboratories and often not available, although there have been advances and field deployment of rapid laboratories. 36 The Cepheid GeneXpert platform, a real-time PCR (RT-PCR) with an automated and integrated configuration that reports faster than conventional RT-PCR methods, has been successfully evaluated in the field. However, the operational requirements are still relatively complex for deployment in truly resource-limited settings: an operator with some laboratory expertise is required for platform and assay validation, quality control, and maintenance.…”

Section: Laboratory and Field Diagnosismentioning

confidence: 99%

What Do We Know About Controlling Ebola Virus Disease Outbreaks?

2017

Retrovirology: Research and Treatment

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The West African Ebola Virus Disease outbreak was unprecedented in size, dwarfing all previous outbreaks by some magnitude. Nearly, more than 28 000 people had been infected, with more than 11 000 deaths recorded. This review article will highlight some of the major public health and therapeutic advances realised during this outbreak, as well as pointing readers to key review articles on the different aspects of disease control. It will describe the multifaceted international response and detail how the response efforts allied traditional public health approaches and novel models of intervention. It will review the shift from a humanitarian response paradigm to real-time evidence-based decision making, including modelling of potential interventions, novel interventional treatment studies, and pragmatic vaccine trials.

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Deployment of the French Military Field Laboratory Dedicated to Ebola Virus Infected Patients in Guinea, January–July 2015

Cited by 8 publications

References 4 publications

Percutaneous dilatational tracheostomy for saturating influx of COVID-19 patients: Experience of military ENT physicians deployed in Mulhouse, France

Percutaneous dilatational tracheostomy for saturating influx of COVID-19 patients: Experience of military ENT physicians deployed in Mulhouse, France

Contribution of the French army health service in support of expertise and research in infectiology in Africa

What Do We Know About Controlling Ebola Virus Disease Outbreaks?

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