Depletion of docosahexanoic acid in erythrocyte membranes of depressive patients

Considerations regarding neuropsychiatric nutritional requirements for intakes of omega-3 highly unsaturated fatty acids

“…They also noted a biological gradient with lower erythrocyte DHA correlated with greater severity of symptoms (r= 0.80, p<0.01). Peet et al (41) also reported a nearly 50% reduction in DHA in the erythrocytes of depressed subjects. Among a community sample of the elderly in Bordeaux, plasma EPA alone was inversely associated with severity of depressive symptoms (42).…”