Dephosphorylation of Adenosine Triphosphate by Concentrates of the Virus of Avian Erythromyeloblastic Leucosis.

Virus or Avian Myeloblastic Leukosis

“…The virus of myeloblastic leukosis displays the property strongly to dephosphorylate adenosine (Green and Beard, 1955a;Mommaerts et al, 1952Mommaerts et al, , 1954 and inosine triphosphates . This is an activity which has not been recognized for any other viral agent.…”

Morphology of Viruses

“…Avian Erythromyeloblastic Leukosis.-One member of the general leukosis complex (104) of chickens (avian leucosis), has been given the above de scriptive label by a group of workers (76,105) at Duke University. Purifica tion of the virus from the plasma of infected birds by differential centrifuga tion revealed the presence of many particles of about 120 mJ.'…”

Relationship of virulent and attenuated rna oncogenic virus antigens to surface antigens of the virus‐transformed cell: Implications for the reverse transcriptase system, the provirus, protovirus and oncogene theories of neoplasia, and the lmmunoprophylaxis of RNA virus‐induced tumors

“…Besides the above-mentioned enzymes, virus-associated enzymes include adenosine triphosphatase (Mommaerts et al, 1952;De-The, 1964), nucleoside triphosphatase and nucleoside triphosphate phosphotransferase (Roy and Bishop, 1971), nucleotide kinase and phosphatase (Mizutani and Temin,197 l), protein kinase (Strand and August,197 l), RNA-nucleoside triphosphate nucleatidyl transferase (Nakata and Sakamoto,197 l), RNA methylase (Gantt et al, 1971), hexokinase and lactic dehydrogenase , transfer RNA synthetases (Erikson and Erikson, 1972) and ofhers. Thelcell derivation of at least some of these virus-associated enzymes is necessary because of the limitation in coding ability of RNA viral nucleic acid with a rholecular weight of about lo7 (Galibert et al, 1966).…”