Dependence on e‐cigarettes and cigarettes in a cross‐sectional study of US adults

Shiffman, Saul; Sembower, Mark A.

doi:10.1111/add.15060

Cited by 44 publications

(34 citation statements)

References 30 publications

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“…The lower AL of Vuse Solo compared to CC is consistent with accumulating evidence for the overall ENDS category. 51,52,55,56 In this study, nicotine uptake within the rst 15 minutes of Vuse Solo use was closer to that of CC use than to nicotine gum use. This pro le suggests the potential for alleviation of smoking urges and cravings and increases the likelihood of product adoption.…”

Section: Discussionmentioning

confidence: 46%

Part One: Abuse Liability of Vuse Solo Relative To Combustible Cigarettes And Nicotine Gum

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et al. 2022

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Abuse liability (AL) of electronic nicotine delivery systems (ENDS) is relevant as the category increases in popularity as a potentially less-harmful alternative to cigarette smoking. AL assessments are important to the FDA in determining if a new product is appropriate for the protection of public health. This paper reports the results for Vuse Solo and high and low AL-comparators evaluated in an open-label, randomized crossover confinement AL study. The confinement design was adapted from previous ambulatory studies of Vuse Solo and included product familiarization sessions before each four-hour test session in which subjective measures, nicotine uptake, and physiological endpoints were assessed following a single 10-minute ad libitum product use session. Product liking, intent to use again, suppression of urge to smoke, and nicotine uptake were lower after use of Vuse Solo compared to cigarettes and higher after use of Vuse Solo compared to nicotine gum. No significant differences in blood pressure or heart rate were observed between the products pre- to post-product use. These data reinforce previous research showing that Vuse Solo has an AL profile lower than that of combustible cigarettes but higher than that of nicotine gum and may have sufficient AL for product adoption by current adult smokers.

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Section: Discussionmentioning

confidence: 46%

Part One: Abuse Liability of Vuse Solo Relative To Combustible Cigarettes And Nicotine Gum

Campbell

Jin

Round

et al. 2022

Preprint

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“…30 Moreover, combustible product use may be associated with greater dependence, which could make cessation more difficult for individuals who use these types of products. 47 As the tobacco and cannabis markets become increasingly diverse, this indicates a need to emphasize the established risks of combustible products (ie, at the far end of the risk continuum 32 ) compared to other types of available products in prevention and intervention efforts to reduce harms to public health.…”

Section: Discussionmentioning

confidence: 99%

Developmental Trajectories of Tobacco/Nicotine and Cannabis Use and Patterns of Product Co-use in Young Adulthood

et al. 2020

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Introduction: Concurrent co-use of tobacco/nicotine and cannabis (T/C) products is common among young people and may increase risks for negative health and psychosocial outcomes, but little is known about developmental patterns of T/C co-use. This study aimed to identify distinct trajectory classes of concurrent T/C co-use from ages 16 to 21 and compare groups on T/C co-use behaviors in young adulthood. Methods: Participants (n = 2497) reported T/C use on annual online surveys from 2015 to 2019 (ages 16-22). We used parallel process growth mixture models to model simultaneous trajectories of past-month cigarette, e-cigarette, smokeless tobacco, and cannabis use and identify latent classes of T/C trajectories. Classes were then compared on types and number of T/C products used and types of T/C co-use in young adulthood. Results: Models revealed 4 T/C classes: Low/No T/C Use, Early Concurrent T/C Co-use, Late Concurrent T/C Co-use, and Tobacco Quitters/Cannabis Maintainers. Compared to other classes, the Early Concurrent T/C Co-use group—individuals with rapid progression to concurrent T/C co-use during adolescence—were more likely to report poly-tobacco use, poly-cannabis use, same-occasion sequential T/C co-use and T/C co-administration (ie, mixing T/C) of both combustible and vaping products in young adulthood. Conclusion: Early progression to concurrent T/C co-use in adolescence is prospectively linked to poly-product use and co-use of T/C products in young adulthood. Prevention efforts targeting co-use of T/C products in adolescence may help to reduce riskier patterns of T/C use and co-use in young adulthood.

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“…The role of nicotine addiction in sustained use of tobacco is well-documented, as is the increased susceptibility of adolescent brains to harms caused by early nicotine exposure – including greater risk of long-term nicotine addiction [ 51 , 57 ]. Some studies comparing dependence associated with use of e-cigarettes and combustible cigarettes have found e-cigarettes to be consistently associated with lower nicotine dependence than cigarette smoking [ 58 ]. However, these studies focused only on adult e-cigarette users and relied on data collected before cartridge-type, high-nicotine-content products entered – and quickly dominated – the e-cigarette market [ 55 ].…”

Section: Resultsmentioning

confidence: 99%

Co-creating opportunities to incorporate cessation for electronic nicotine delivery systems in family medicine – a qualitative program evaluation

et al. 2021

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Background The number of Americans who use tobacco has decreased in the twenty-first century, but electronic nicotine delivery systems (ENDS) have increased the complexity of treating tobacco dependence. The experiences of 18 family medicine practices were explored and opportunities to improve ENDS cessation were co-created in this study. Methods Eighteen family medicine practices were enrolled into an implementation project to incorporate ENDS cessation into their practice. The participants’ experiences were explored throughout the project using an iterative qualitative approach. The research team provided technical assistance. Semi-structured group interviews and focus groups were held with participants at the beginning, middle, and end of the project to explore participants’ experiences. The collective knowledge and experiences of participants, expert consultants and the research team were fused together to co-create opportunities to improve ENDS cessation. Results Nine opportunities to improve ENDS cessation were identified in three larger categories. The first category was leading change. This included: creating a vision for change to establish buy-in from key stakeholders and educate health care professionals to improve their confidence to address ENDS. The second category was creating processes. This included: establishing criteria for screening and quality improvement for ENDS cessation; being specific when asking about ENDS; creating electronic health record systems to support incorporating ENDS cessation; using chart audits if electronic health records cannot support incorporating ENDS into tobacco cessation; and assigning roles and responsibilities to members of the clinical care team. The third category was assisting patients who use ENDS. This included: educating patients and their parents/caregivers about ENDS and their potential harms, avoiding dual use, and developing a plan to quit. Conclusions This study highlights challenges and opportunities for incorporating ENDS cessation into family medicine. The opportunities outlined here provide a practical approach which is rooted in the experiences of family physicians and their clinical care teams working to improve how they address ENDS and based on peer reviewed literature and expert input. Improving how ENDS are addressed in family medicine will require more than clinical expertise. It will also require leadership skills and the ability to create process improvements. Trial registration Not applicable

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Dependence on e‐cigarettes and cigarettes in a cross‐sectional study of US adults

Cited by 44 publications

References 30 publications

Part One: Abuse Liability of Vuse Solo Relative To Combustible Cigarettes And Nicotine Gum

Part One: Abuse Liability of Vuse Solo Relative To Combustible Cigarettes And Nicotine Gum

Developmental Trajectories of Tobacco/Nicotine and Cannabis Use and Patterns of Product Co-use in Young Adulthood

Co-creating opportunities to incorporate cessation for electronic nicotine delivery systems in family medicine – a qualitative program evaluation

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