Dependence of bubble size and peak rarefractional pressure on maximum bubble response during therapeutic ultrasound histotripsy

Abstract

First and foremost and I would to acknowledge Dr. Timothy Bigelow. Through his intelligence and hard work he was rewarded a much deserved career grant that has been able to fund my graduate experience. He has challenged me and stretched my brain to places I did not think possible, and done so in the kindest most patient fashion. I am forever grateful. Special thanks to Charles Church (Associate Research Professor, University of Mississippi, Oxford, MS) for providing code that could be modified to calculate the bubble response. This work is supported by NSF grant Award ECCS-0643860 "CAREER: Ultrasound Histotripsy System Development to Improve Cancer Treatment." I would also like to thank Dr. Scott McClure in Veterinary Clinical Sciences. He kindly provided tissue samples for this study on demand.