Deodorization of Laboratory Animal Facilities by Ozone.

Pan, Tien Mei; Shimoda, Kouji; Cai, Yi; Kiuchi, Yoshihiro; Nakama, Kazumasa; Akimoto, Toshio; Nagashima, Yasuaki; Kai, Masakazu; Ohira, Michio; Saegusa, Junzo; Kuhara, Takatoshi; Maejima, Kensaku

doi:10.1538/expanim.44.255

Cited by 9 publications

(7 citation statements)

References 3 publications

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“…Owing to these advantages, there are many applications of O 3 in the industry, e.g. in the sterilization of perishables, facility deodorization, and purification of wastewater [7][8][9]. However, because of the decomposing reaction, ozone is difficult to preserve [10].…”

Section: Introductionmentioning

confidence: 99%

Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates

Hatsugai

Nakayama

Tomura³

et al. 2020

Chem Eng & Technol

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Ozone (O 3) has many industrial applications such as in sterilization. One of the long-term O 3 preservation methods is molecular storage in clathrate hydrate. In this study, an experimental system was developed for continuously forming O 3 + O 2 + CO 2 hydrates. The parameters that affect the continuous operation of the system and that lead to increases in the concentration of O 3 in the hydrates were also experimentally evaluated, implementing the method of quality engineering. After optimizing these operating parameters, the O 3 storage capacity in the hydrates was measured to be 0.26 wt % at 2 h of total operation time. By X-ray diffraction, it was found that the produced sample contained hydrates, and longterm preservation for 6 months was possible at the temperature of general freezing warehouses.

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Section: Introductionmentioning

confidence: 99%

Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates

Hatsugai

Nakayama

Tomura³

et al. 2020

Chem Eng & Technol

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“…Various odors, including predator odor and ammonia, are well-known stressors for the rat and lead to a cortisol release and BP increase (22,25). We used ammonia as a stressor as it is a naturally occurring stressor, being present in rat secretions (26). Furthermore, it is easy to administer and remove.…”

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confidence: 99%

Association of Birth Weight with Cardiovascular Parameters in Adult Rats During Baseline and Stressed Conditions

et al. 2006

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Low birth weight (LBW) due to intrauterine growth restriction (IUGR) in humans is associated with increased blood pressure (BP) in adulthood. In Western countries, IUGR is based on uteroplacental dysfunction. We used an animal model of uteroplacental dysfunction to evaluate this correlation. We hypothesize that IUGR increases baseline BP and alters the BP response to acute stress, which may explain BP differences in previous studies using stressful methods to obtain BP. IUGR was induced by bilateral uterine artery ligation in pregnant Wistar rats according to a modified method of Wigglesworth. BP was measured in the offspring using telemetry, allowing for unstressed measurements in conscious animals. Cardiovascular data were obtained at the age of 12 wk during baseline and acute olfactory stress induced by an ammonia gauze. Rats born after IUGR had a lower birth weight versus controls and did not completely catch up in weight. At baseline, systolic BP (SBP), mean arterial pressure (MAP), and pulse pressure (PP) were elevated in IUGR rats versus controls, by 8, 6, and 5 mm Hg, respectively. There was a strong negative correlation between birth weight and SBP and between birth weight and PP. During acute stress, there was a tendency to reach a higher peak in SBP and to need a longer period to recover in IUGR animals. We conclude that IUGR is associated with increased baseline BP. I UGR leads to LBW, which is linked to an increased risk of various chronic diseases in adulthood (1-4). Numerous studies have described the association between LBW and hypertension (for review, see Huxley et al. (5)). The pathways that may lead to a rise in BP are not fully understood (6 -18).Several previous authors have studied BP in growthrestricted animals (19). In these studies, BP is commonly measured indirectly using the tail-cuff method. This method entails restraining and preheating the animal, which leads to increased BP, heart rate (HR), and plasma levels of epinephrine and norepinephrine (20). In fact, restraints on laboratory animals have been used as a stressor (21). Results obtained from these studies should therefore be interpreted with caution. The described raised BP in IUGR animals might reflect a different stress response rather than a raised baseline BP.BP can be measured both directly as in a nonstressed manner by telemetry (20). Previously, only two reports using telemetry have addressed the effect of IUGR on BP in rats. Tonkiss et al. (22) found a small rise in baseline diastolic BP (DBP) but not in SBP in IUGR rats. They also described a marked difference in the response to acute stress with a greater increase in DBP and SBP in IUGR rats. Jansson and Lambert (23) found no evidence for BP elevation after IUGR. In these studies, different models for IUGR were used. For a review of currently applied IUGR models, see Holemans et al. (19). Tonkiss et al. (24) applied an IUGR model based on prenatal protein restriction, which might not be representative of the human situation. In Western countries, the lead...

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“…Dissolved ozone in water is an environmentally clean and powerful oxidant, with an absence of harmful residues, which has found use in sterilization/sanitization, 1 deodorization, 2 decolorization, 3 and the treatment of potable water/wastewater. 4,5 As ozone decays in water with a half-life of ca.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Ozone Generation Using Compacted High Pressure High Temperature Boron Doped Diamond Microparticle Electrodes

Wood

Rodríguez

Tully

et al. 2021

Preprint

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Electrochemical ozone production (EOP) from water is an attractive, green technology for disinfection. Boron doped diamond (BDD) electrodes, grown by chemical vapor deposition (CVD), have been widely adopted for EOP due to their wide anodic window in water and excellent chemical and electrochemical stability. High pressure high temperature (HPHT) synthesis, an alternative growth technique used predominantly for the high-volume synthesis of nitrogen doped diamond microparticles, has been seldom employed for the production of conductive BDD electrodes. In this letter, we demonstrate, for the first time, the use of BDD electrodes fabricated from HPHT conductive BDD microparticles for EOP. The BDD microparticles are first compacted to produce freestanding solid electrodes and then laser micromachined to produce a perforated electrode. The HPHT BDD electrodes are shown to exhibit high EOP, producing 2.23 ± 0.07 mg L-1 of ozone per ampere of current, at consistent levels for a continuous 20 hr period with no drop off in performance.

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Deodorization of Laboratory Animal Facilities by Ozone.

Cited by 9 publications

References 3 publications

Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates

Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates

Association of Birth Weight with Cardiovascular Parameters in Adult Rats During Baseline and Stressed Conditions

Electrochemical Ozone Generation Using Compacted High Pressure High Temperature Boron Doped Diamond Microparticle Electrodes

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Deodorization of Laboratory Animal Facilities by Ozone.

Cited by 9 publications

References 3 publications

Development and Continuous Operation of a Bench‐Scale System for the Production of O3 + O2 + CO2 Hydrates

Development and Continuous Operation of a Bench‐Scale System for the Production of O3 + O2 + CO2 Hydrates

Association of Birth Weight with Cardiovascular Parameters in Adult Rats During Baseline and Stressed Conditions

Electrochemical Ozone Generation Using Compacted High Pressure High Temperature Boron Doped Diamond Microparticle Electrodes

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Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates

Development and Continuous Operation of a Bench‐Scale System for the Production of O₃ + O₂ + CO₂ Hydrates