Dentist's knowledge regarding oral mucosal lesions: Revealing the diagnostic dilemma

Choudhary, Anuraag B; Deshmukh, Ajinkya; Chaudhary, Mayur; Chaudhary, Shweta; Deshmukh, Atul; Chaudhary, Trupti

doi:10.4103/ijhas.ijhas_29_18

Cited by 2 publications

(2 citation statements)

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“…Thin-film composite (TFC) nanofiltration (NF) membranes have a wide range of applications not only for typical water purification and brackish water desalination but also for non-aqueous processes in pharmaceutical and biotechnology industries. , The global NF membrane market value was reported to be approximately $643 million in 2017 and it is estimated to reach $955 million by 2025 with a 5.4% compound annual growth rate between 2018 and 2025 . This clearly indicates the increasing use of NF membranes for industrial applications in the years to come.…”

Section: Introductionmentioning

confidence: 99%

New Concept of Thin-Film Composite Nanofiltration Membrane Fabrication Using a Mist-Based Interfacial Polymerization Technique

Seah

Khoo

Lau

et al. 2021

Ind. Eng. Chem. Res.

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The conventional interfacial polymerization (CIP) technique used for preparing thin-film composite (TFC) nanofiltration membranes typically requires a large amount of monomers during polyamide (PA) synthesis where most of the monomers are discarded after cross-linking. Thus, a new fabrication concept is proposed in this work to synthesize a PA layer via a mist-based interfacial polymerization (MIP) technique where only a small amount of aqueous solution is dispersed as mist. This approach also eliminates the rubber-rolling step in CIP. In addition to forming a thinner and looser PA structure, the piperazine solution required in the IP reaction is significantly reduced, that is, 17 times lower than that of CIP. The microdroplet dispersion approach in MIP could form a higher cross-linked PA due to the high polymerization interface besides forming a higher free-volume selective layer due to the disruption in the PA repeat structure. Our findings revealed that the newly developed mist-based TFC membrane could achieve 9.08 L/m2·h·bar pure water permeability and 97.2% Na2SO4 rejection coupled with a complete flux recovery rate. As a comparison, the conventional TFC membrane only attained 2.84 L/m2·h·bar and 95.7%, respectively. The MIP technique could also be potentially considered for developing a nanofiller-incorporated TFC membrane due to the absence of the rubber-rolling step.

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Section: Introductionmentioning

confidence: 99%

New Concept of Thin-Film Composite Nanofiltration Membrane Fabrication Using a Mist-Based Interfacial Polymerization Technique

Seah

Khoo

Lau

et al. 2021

Ind. Eng. Chem. Res.

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“…First, when the ulcer attacks and the pain is severe and brings great inconvenience to daily life. Secondly, when the oral ulcer is recurrent, it will directly affect the immune function of the whole organism of the patient [ 35 ]. Systemic complications include halitosis, chronic pharyngitis, constipation, fever, headache, dizziness, swollen lymph nodes, and loss of vision.…”

Section: Oral Ulcersmentioning

confidence: 99%

Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers

et al. 2022

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Oral ulcers affect oral and systemic health and have high prevalence in the population. There are significant individual differences in the etiology and extent of the disease among patients. In the treatment of oral ulcers, nanofiber films can control the drug-release rate and enable long-term local administration. Compared to other drug-delivery methods, nanofiber films avoid the disadvantages of frequent administration and certain side effects. Electrospinning is a simple and effective method for preparing nanofiber films. Currently, electrospinning technology has made significant breakthroughs in energy-saving and large-scale production. This paper summarizes the polymers that enable oral mucosal adhesion and the active pharmaceutical ingredients used for oral ulcers. Moreover, the therapeutic effects of currently available electrospun nanofiber films on oral ulcers in animal experiments and clinical trials are investigated. In addition, solvent casting and cross-linking methods can be used in conjunction with electrospinning techniques. Based on the literature, more administration systems with different polymers and loading components can be inspired. These administration systems are expected to have synergistic effects and achieve better therapeutic effects. This not only provides new possibilities for drug-loaded nanofibers but also brings new hope for the treatment of oral ulcers.

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Dentist's knowledge regarding oral mucosal lesions: Revealing the diagnostic dilemma

Cited by 2 publications

References 1 publication

New Concept of Thin-Film Composite Nanofiltration Membrane Fabrication Using a Mist-Based Interfacial Polymerization Technique

New Concept of Thin-Film Composite Nanofiltration Membrane Fabrication Using a Mist-Based Interfacial Polymerization Technique

Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers

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