Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin

West, Nicola; Lussi, Adrian; Seong, Joon; Hellwig, Elmar

doi:10.1007/s00784-012-0887-x

Cited by 220 publications

(208 citation statements)

References 116 publications

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“…Dental erosion begins by softening of the surface and is followed by an irreversible dissolution leading to loss of tooth volume and dentine exposure caused by intrinsic and extrinsic factors 7 . These factors originate from the backflow of gastric fluid and dietary acids.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with dentine hypersensitivity severity in Colombian dental patients.

López¹,

España²,

Bastidas³

et al. 2016

J Oral Res

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Factors associated with dentine hypersensitivityseverity in Colombian dental patients.Cite as: López L, Espana P, Bastidas R, Fuelagan J & Mafla AC. Factors associated with dentine hypersensitivity severity in Colombian dental patients. J Oral Res 2016; 5(2): 63-70. Abstract: Introduction: The aim of this study was to determine the prevalence of dentine hypersensitivity (DH) and examine associated etiological factors related to the severity of DH in dental clinic patients treated at the School of Dentistry at Universidad Cooperativa de Colombia, Pasto, Colombia. Materials and Methods: A cross-sectional study was designed in which three hundred and thirty three patients aged 15 to 44 years old were assessed for the presence and severity of DH. The dentine hypersensitivity diagnosis was based on self-reported sensitivity and a clinical examination. The questionnaire included socio-demographic information, data about oral health habits and acidic dietary intake. A descriptive analysis was performed and the association between DH severity and risk factors was determined using an ordinal logistic regression model. Results: Dentine hypersensitivity was detected in 88 out of 333 (26.4%) subjects (95% CI: 21.83-31.56). The pH of natural juices (OR=6.013; 95% CI: 0.995-36.319, p=0.051) and pH of alcohol beverages (OR= 7.800; 95% CI: 2.282-26.658, p=0.001) were significantly associated with the severity of dentine hypersensitivity. Conclusions: The results indicated that the prevalence of dentine hypersensitivity in these patients was consistent with previous reports. Furthermore, the severity of DH was influenced by acidic diet. These results suggest that dental counseling should be provided to all patients as well as to those with dentine hypersensitivity to prevent the occurrence of this oral health problem and the severity of symptoms.

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Section: Introductionmentioning

confidence: 99%

Factors associated with dentine hypersensitivity severity in Colombian dental patients.

López¹,

España²,

Bastidas³

et al. 2016

J Oral Res

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“…It is now widely acknowledged that dentin hypersensitivity derives from exposed dentin tubules, where stimuli excite pulp cells as proposed by BrannstrÖm's hydrodynamic theory. 2,3 According to that theory, the diameter of the exposed tubules and their density are the factors that mainly influence hypersensitivity, 4 as already highlighted by Yoshiyama et al 5 Finding a way to close the orifices of the tubules could therefore decrease pain perception. Since this discovery, many therapeutic approaches to dentin hypersensitivity have been employed.…”

Section: Introductionmentioning

confidence: 98%

Calcium phosphate nanoparticles reduce dentin hypersensitivity: a randomized, placebo-controlled split-mouth study

Ionescu¹,

Varoni²,

Cazzaniga³

et al. 2017

EDUJ

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Introduction: Modern strategies for dental remineralization and prevention of dentin hypersensitivity are increasingly based on biomimetic materials. The aim of this study was to assess the clinical efficacy of a calcium-phosphate nanoparticles-based dentin desensitizer (DD, Teethmate Desensitizer, Kuraray Noritake, Japan). methodology: 25 patients, requesting treatment after reporting sensitivity of non-carious cervical lesions and dental abrasions were recruited. Inclusion criteria were: response score ≥6 on a 10 cm-long visual analog scale (VAS) for 1+ teeth in each of two quadrants. Exclusion criteria were: presence of systemic diseases, ongoing analgesic therapy, pregnancy, presence of carious or pulpal lesions, poorly contoured restorations, enamel cracks, active periodontitis and ongoing use of desensitizing agents. The response was determined to 2 s air blast. VAS scores were collected at t=0 (PRE), immediately after treatment with the DD (POST), after 1 week, and after 1, 3 and 6 months. Half of the sites in each patient (split-mouth) were randomly treated with a placebo, and scores collected until after 1 week. The DD was then applied to the placebo sites. results: Both DD and placebo significantly decreased VAS scores on POST confronted to PRE (p<0.0001), showing similar efficacy (35% and 28%, respectively). DD application further decreased scores after 1 week (63%) while placebo application did not show significant differences confronted to POST (p=0.09). DD scores maintained throughout the observational period the levels obtained after 1 week. Conclusion: The tested DD effectively reduced dentin hypersensitivity during 6-month followup, after one single application. Biomimetic desensitizers may be an effective solution to dentin hypersensitivity.

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“…1 DH-related discomfort may have a significant negative impact on an individual's daily life, as it may cause difficulties in eating, drinking and speaking. 2 Due to its high prevalence, significant efforts have been made to understand the etiology and mechanisms involved in DH development.…”

Section: Introductionmentioning

confidence: 99%

Ultramorphological and chemical characterization of dentin surfaces after application of two desensitizing toothpastes

Vinagre¹,

Fagulha²,

Cardoso³

et al. 2017

j.rpemd

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Objectives: To evaluate dentin tubule obliteration after application of two different desensitizing toothpastes using scanning electron microscopy (SEM) for ultramorphological analysis and energy dispersive X-ray spectroscopy (EDX) for chemical evaluation.Methods: Five dentin discs were sectioned into four quarters; surfaces were etched with 6% citric acid for 2 minutes and equally distributed into four groups. In G1 (control) no treatment was performed; dentin surfaces were brushed twice-daily during 14 days with artificial saliva (G2), a combined stabilized stannous fluoride, sodium hexametaphosphate and silica (SFSH) toothpaste (G3) and a calcium sodium phosphosilicate (CSFS) toothpaste (G4), under a standardized protocol. All specimens were analyzed by SEM and EDX and tubule occlusion was scored. Statistical analysis was performed using Kruskal-Wallis (p<0.05).Results: Score distribution across groups consistently increased from G1 to G4, being the last the most consistent group. Statistical between-treatment comparisons for 750-fold and 2000-fold magnification revealed significant differences between groups (p=0.009 and p=0.002, respectively). For both magnifications, post-hoc analysis adjusted for multiple comparisons only indicated statistically significant differences between G1 and G4 (p=0.012 and p=0.001, respectively). Chemical analysis revealed high levels of carbon, oxygen and nitrogen for G1. For G2 an increase of the levels of the phosphorous and calcium elements and a drop of oxygen and carbon levels was registered. G3 and G4 showed a surface layer mainly composed of calcium and phosphorous.Conclusions: Both desensitizing toothpastes induced high levels of tubule occlusion with consistent phosphorus and calcium deposition over dentin surface. Caracterização ultramorfológica e química de superfícies dentinárias após aplicação de duas pastas dentífricas dessensibilizantes Palavras-chave:Hipersensibilidade dentária Túbulos dentários Raios X por dispersão em energia Microscopia electrónica de varrimento Pasta dentífricaObjectivos: Avaliar a obliteração dos túbulos dentinários após a aplicação de duas pastas dentífricas dessensibilizantes, usando microscopia eletrónica de varrimento (MEV) e espectroscopia de raios X por dispersão em energia (EDX).Métodos: Foram seccionados cinco discos de dentina em quatro quartos, condicionados com ácido cítrico a 6% por 2 minutos e distribuídos equitativamente em quatro grupos: No G1 (controlo) não se efetuou qualquer tratamento; as superfícies dentinárias foram escovadas duas vezes por dia durante 14 dias com saliva artificial (G2), uma pasta de fluoreto estanhoso estabilizado, hexametafosfato de sódio e sílica (SFSH) (G3) e uma pasta de fosfosilicato de sódio e cálcio (CSFS) (G4). As amostras de cada grupo foram quantificadas por MEV e EDX.Na análise estatística aplicou-se o teste de Kruskal-Wallis (p<0,05).Resultados: O grau de oclusão tubular aumentou de G1 até G4, sendo este último o mais consistente.Para as ampliações de 750x e 2000x foram encontradas diferenç...

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Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin

Cited by 220 publications

References 116 publications

Factors associated with dentine hypersensitivity severity in Colombian dental patients.

Factors associated with dentine hypersensitivity severity in Colombian dental patients.

Calcium phosphate nanoparticles reduce dentin hypersensitivity: a randomized, placebo-controlled split-mouth study

Ultramorphological and chemical characterization of dentin surfaces after application of two desensitizing toothpastes

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