Dental treatment before haematopoietic stem cell transplantation - a service evaluation

Wilson-Dewhurst, Charlotte; Kwasnicki, Andrew; Macpherson, Avril; Thompson, Shelagh

doi:10.1038/s41415-021-2841-2

Cited by 1 publication

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Wilson‐Dewhurst and colleagues reported high levels of pretransplant dental pathology in 74 patients with HCT with 34% requiring dental extraction. Notably, only 4% were treated with periodontal therapy (Wilson‐Dewhurst et al, 2021). Other studies suggest much greater periodontal need in the HCT population.…”

Section: Discussionmentioning

confidence: 99%

Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation

Dean,

Lee,

Cutler

et al. 2023

Oral Diseases

View full text Add to dashboard Cite

IntroductionDental examination and stabilization are performed prior to allogeneic hematopoietic cell transplantation to decrease infection risk during neutropenia. Burden of dental disease and treatment need is not well characterized in this population.ObjectivesThis report describes the dental status of a cohort of patients within the Chronic Graft‐versus‐Host Disease Consortium and treatment rendered prior to transplant.MethodsThe cohort included 486 subjects (Fred Hutchinson: n = 245; Dana‐Farber: n = 241). Both centers have institutional‐based dental clearance programs. Data were retrospectively abstracted from medical records by calibrated oral health specialists.ResultsThe median age at transplant was 55.9 years, 62.1% were male, and 88% were white. Thirteen patients were edentulous (2.7%). The mean teeth among dentate patients before clearance was 26.0 (SD, 4.6). Dental findings included untreated caries (31.2%), restorations (91.6%), endodontically treated teeth (48.1%), and dental implants (5.7%). Pretransplant procedures during clearance included endodontic therapy (3.6%; mean = 0.1 teeth), restorations (25.1%; mean = 0.7), dental prophylaxis (59.2%), scaling/root planing (5.1%), and extraction (13.2%; mean = 0.3). The mean teeth after clearance was 25.6 (SD, 5.0).ConclusionsRetrospective analysis of pre‐AlloHCT dental data in subjects at two large transplant centers identified low levels of dental need. Findings suggest high access to care.

show abstract

Section: Discussionmentioning

confidence: 99%