Dental sedation for patients with intellectual disability: a prospective study of manual control versus Bispectral Index-guided target-controlled infusion of propofol

Abstract

Propofol sedation using BIS-guided TCI is a useful and safe method in the management of patients with intellectual disability.

Complications of IV sedation for dental treatment in individuals with intellectual disability

“…In this study intravenous sedation using Propofol was applied for dental patients with intellectual disability similar to other reports [4][5][6]. Propofol was given according to published guideline [7,8] 1 mg/kg IV Propofol bolus Incremental top ups of 0.25 mg/kg Propofol as required, as study of Newstead and his colleagues [9].…”

Clinical effectiveness and cost-effectiveness of depth of anaesthesia monitoring (E-Entropy, Bispectral Index and Narcotrend): a systematic review and economic evaluation

“…Because of finite time and resources we prioritised the largest of these for inclusion in the review (a trial of around 5000 patients, specifically designed to assess intraoperative awareness 40 ). The other three were smaller trials (80 patients, 41 40 patients, 42 and 20 patients 43 respectively) and their inclusion in the review was unlikely to change the findings. In summary, a total of 22 RCTs were included in this systematic review.…”

Monitoring and delivery of sedation

“…For dental procedures in patients with intellectual disability, propofol TCI titrated to BIS TM resulted in less propofol usage and faster times to eye opening compared with manual administration titrated to clinical signs. 105 Propofol TCI administered for deep sedation ERCP resulted in faster emergence and less-frequent oxygen desaturations compared with a manual-controlled group. 106 Remifentanil TCI compared with manual administration for colonoscopy showed less concomitant propofol delivery and a lower incidence of apnoea and respiratory depression.…”