Dental Panoramic Radiographic Indices as a Predictor of Osteoporosis in Postmenopausal Saudi Women

Abstract

BackgroundMany oral presentations of osteoporosis-a bone metabolic disease-were recorded. Thus, we aimed to assess panoramic radiomorphometric indices with bone mineral density (BMD) values among Saudi postmenopausal women and its importance in the prediction of osteoporosis.MethodsA total of 431 Saudi women were enrolled in this study. Panoramic radiographs were obtained at the time of BMD measurement. Subjects were fatherly classified into; normal BMD, osteopenia, and osteoporosis groups. Serum follicle-stimulating hormone, luteinizing hormone (LH), estradiol (E2), 25-hydroxy-vitamin D (25[OH]D) and intact-parathyroid hormone were measured. Moreover, serum creatinine, calcium, and phosphate, together with serum osteocalcin (s-OC), procollagen type I N-terminal propeptide (s-PINP) and cross-linked C-terminal telopeptide of type 1 collagen (s-CTX) were measured. Receiver-operator curve (ROC) curve analysis for use of mandibular cortical width (MCW), panoramic mandibular index (PMI), and maxillary-mandibular ratio (M/M ratio) to differentiate women with osteoporosis or osteopenia from normal subjects was calculated. Cut off values of 4.6 at T score <−1 and 4.1 at T score ≤−2.5 were used.ResultsBody mass index is significantly low in the osteoporotic group. There is no significant difference in serum levels of LH, E2, calcium, phosphate, and 25(OH)D between the studied groups. Moreover, s-OC, C-terminal propeptide of procollagen type I, s-PINP, s-CTX, and urinary-CTX are significantly higher in osteoporosis than normal and osteopenia groups. ROC curve analysis revealed that MCW and PMI showed significant data while M/M ratio is non-significant.ConclusionsIt could be concluded that MCW as an important panoramic radiographic parameter can be used for prediction and diagnosis of osteoporosis in postmenopausal Saudi women with low BMD.

Bone Turnover Markers and Bone Mineral Density to Predict Osteoporotic Fractures in Older Women: A Retrospective Comparative Study

“…There was no statistically significant difference in ALP, P, and Ca between the two groups (P > 0.05), which may be because levels of mineral salts such as P and Ca tend to be normal in patients with primary osteoporosis; this was consistent with findings by Balto et al 27 . Serum ALP can reflect some bone ALP but cannot fully represent bone ALP indicators.…”

Osteoporosis of the Jaws and its Diagnostic Methods: Review of the Literature

“…Según la OMS, el diagnóstico de osteoporosis con DXA debería ser de preferencia en columna lumbar y cadera; y sugiere un seguimiento cada 1 a 2 años de acuerdo a la gravedad de dicha enfermedad y la verificación de la efectividad del tratamiento instaurado mediante una DXA central (55). La DXA es una técnica radiográfica costosa, que implica mayor radiación y no es considerada como un examen de rutina en detección de osteoporosis en mujeres posmenopáusicas (56,57).…”

Nilai ketebalan kortikal mandibula pada anak dan remaja terinfeksi HIV

“…11,12 Penggunaan radiograf panoramik sebagai alat atau metode screening dipertimbangkan untuk menilai bone mineral density karena bersifat costeffective dan tersedia secara rutin, walapun idealnya memerlukan konfirmasi lebih lanjut dengan DXA dan marker biomekanik. 13 Sama dengan metode DXA, radiograf panoramik dapat digunakan untuk menganalisis rendahnya nilai BMD pada rahang yang terkait dengan beberapa kondisi, termasuk kondisi infeksi HIV. Beberapa indeks pengukuran yang sering digunakan untuk memprediksi nilai BMD yang rendah pada pasien dengan kondisi tertentu seperti mandibular cortical index (MCI), panoramic mandibular index (PMI), mentale index (MI), antegonial index (AGI), dan gonial index (GI).…”