Dental panoramic indices and fractal dimension measurements in osteogenesis imperfecta children under pamidronate treatment

Abstract

Children with OI presented cortical bone alterations after PAM treatment. Both MCW and the FD of the cortical bone were higher in children with OI after PAM treatment. It is argued that cortical bone should be considered for analyzing patients with OI, as well as to monitor the progress of PAM treatment.

Distributional Variations in the Quantitative Cortical and Trabecular Bone Radiographic Measurements of Mandible, between Male and Female Populations of Korea, and its Utilization

“…Several recent studies reported that the findings of cortical bone are more reliable than those of the trabecular bone for the diagnosis of osteoporosis [13, 28, 29]. For osteoporosis in Brazilian male and female subjects, MCW and FD analyses of mandibular cortical bone were found to be more reliable than that of anterior and inferior regions of the trabecular bone [13].…”

“…FDs of the trabecular bone are widely used to identify the complexity and structure of the bone. It is calculated at various anatomical sites using different imaging modalities to observe the changes in bone pattern [29]. Watanabe at al reported that the FD of male group showed a higher degree of trabecular bone architecture and indicated that the structure of their bone is less prone to osteoporotic fractures [32].…”

“…Furthermore, the lack of previous studies on the association of mandibular variables with MCI categories for both genders has made it difficult for us to compare our results directly. Moreover, most studies described potential indicators on radiographs using small sample populations of men and women [12, 13, 15, 17, 20, 21, 23, 26, 28, 29, 32], except a few studies that used larger sample size [14, 16, 27, 31], which limited comparison of results from this study. Although data on the subject’s age and gender were accessible, there were no other anthropomorphic data, such as height, weight, and medical data, available for the estimation of bone strength.…”

Decrease in Mandibular Cortical in Patients With Type 1 Diabetes Mellitus Combined with Poor Glycemic Control

“…Much has been studied about bone quality of dental structures of individuals with systemic conditions that may result in decreased BMD, such as osteoporosis (4), postmenopause (10), celiac disease (11) and osteogenesis imperfect (12). However, there are no studies with radiomorphometric analysis in individuals with T1DM.…”

Utilização de Índices Radiomorfométricos em Exames de Imagem

“…Procurando verificar a relação dos índices radiomorfométricos em radiografias panorâmicas de crianças com diferentes tipos de osteogênese imperfeita, em tratamento com pamidronato intravenoso, conclui-se que, para este grupo de risco, as crianças apresentam corticais mandibulares mais finas e porosas no início do tratamento, e que a melhoria da qualidade do osso cortical pós-tratamento pode ocorrer conforme o tipo de osteogênese imperfeita e número de ciclos de pamidronato. A análise da densidade óssea torna-se de extrema importância para a avaliação do progresso da utilização de pamidronato intravenoso 15 . Novos estudos são necessários para verificar se esses índices podem também predizer o risco de fraturas por osteoporose e elucidar se, em homens idosos, os índices radiomorfométricos possuem a mesma aplicabilidade que a observada em mulheres na pós-menopausa 7 .…”