Dental implants with the periodontium: A new approach for the restoration of missing teeth

Lin, Chen‐Ju; Dong, Qingshan; Wang, Lei; Zhang, Jun-Rui; Wu, Li-An; Liu, Baolin

doi:10.1016/j.mehy.2008.08.018

Cited by 9 publications

(6 citation statements)

References 24 publications

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“…This to a certain extent reflects a long term effect of different prosthetic configurations on the bone quality, though such a fixed partial denture, unlike implant supported structures, does not directly involve contact and osseointegration with the bone. 24,25,37 It should be noted that prosthetic dentistry has become more than the replacement of missing teeth; the preservation of the periodontium has been widely accepted as being vital in the overall success of the FPD, 12,38 but hitherto little regard has been given to the preservation of the bone quality and quantity underlying the FPD which intuitively is also critical in the long term success of the prosthesis and maintenance of best possible oral health. A secondary consideration is the one concerning the issue of the patient's future prosthetic requirements; the preservation of alveolar bone increases the success of implants if the desire or need (in the case of abutment failure) ever eventuates.…”

Section: Discussionmentioning

confidence: 99%

“…Application of this equation was from the well-established long bone remodelling theories. Recent research efforts and validation of remodelling simulation allows us to extent them to the mandibular bone 11,[24][25][26] . In our FE models, the heterogeneous Young's modulus was presented in individual tetrahedral element as per apparent density value.…”

Section: Finite Element Analysismentioning

confidence: 99%

See 1 more Smart Citation

A comparative mechanical and bone remodelling study of all-ceramic posterior inlay and onlay fixed partial dentures

Field¹,

Li²,

Li³

et al. 2012

Journal of Dentistry

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Section: Discussionmentioning

confidence: 99%

Section: Finite Element Analysismentioning

confidence: 99%

A comparative mechanical and bone remodelling study of all-ceramic posterior inlay and onlay fixed partial dentures

Field¹,

Li²,

Li³

et al. 2012

Journal of Dentistry

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“…Numerous attempts to reconstruct periodontal tissues around dental implants revealed the challenge of avoiding fibrous tissue encapsulation and the formation of functional cementum on the implant surface [7] .…”

Section: Periodontal Tissue Regenerationmentioning

confidence: 99%

“…However, osseointegration represents a direct connection between the implant and bone tissue and lacks the periodontium and cementum tissues present in naturally formed teeth, which function to cushion and modulate the mechanical stress of mastication. Therefore, strategies to generate dental implants with associated periodontal tissues have become a new approach in tooth replacement therapies [7] .…”

mentioning

confidence: 99%

Dental Tissue Regeneration – A Mini-Review

Yen

Yelick²

2010

Gerontology

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Background: With today’s 21st century technological advancements, it is expected that individuals will either retain their natural teeth or obtain functional tooth replacements throughout their entire life. Modern dental therapies for the replacement of missing teeth largely utilize partial or complete dentures and titanium implants capped with prosthetic crowns. Although these prostheses serve a purpose, they are not equivalent, neither in function nor aesthetics, to natural teeth. Recent progress in dental tissue engineering has lent significant credibility to the concept that biological replacement teeth therapies may soon be available to replace missing teeth. Objective: In this review, we summarize the emerging concepts of whole-tooth replacement strategies, using postnatal dental stem cells (DSCs) and dental tissue engineering approaches. Methods: We provide a thorough and extensive review of the literature. Results: Current approaches to achieve clinically relevant biological replacement tooth therapies rely on the cultivation of DSCs capable of relaying odontogenic induction signals, through dental epithelial-mesenchymal cell interactions. DSC expansion and differentiation can be achieved by programming progenitor stem cells to adopt dental lineages, using instructive, bioengineered scaffold materials. Periodontal ligament regeneration in particular has demonstrated significant progress recently, despite the somewhat unpredictable clinical outcomes, with regard to its capacity to augment conventional metallic dental implants and as an important component for whole-tooth tissue engineering. Following recent advances made in DSC and tissue engineering research, various research groups are in the midst of performing ‘proof of principle’ experiments for whole-tooth regeneration, with associated functional periodontal tissues. This mini-review focuses on recent and promising developments in the fields of pulp and periodontal tissue DSCs that are of particular relevance for dental tissue and whole-tooth regeneration. Conclusion: Continued advances in the derivation of useable DSC populations and optimally designed scaffold materials unequivocally support the feasibility of dental tissue and whole-tooth tissue engineering.

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“…To overcome these disadvantages, the concept of osseointegration was introduced in the 1950s by Per-Ingvar Branemark, who observed the direct structural and functional bond formation between bone and titanium. However, osseointegration represents a direct connection between the implant and bone tissue and lacks the periodontium and cementum tissues present in naturally formed teeth, which function to cushion and modulate the mechanical stress of mastication (6). Hence, the need of an alterntaive restorative therapy, which may provide for a better substitute for natural teeth is inevitable.…”

Section: Introductionmentioning

confidence: 99%

From Stem to Roots: Tissue engineering in Endodontics

Chandki¹,

Kala²,

Banthia³

2012

J Clin Exp Dent

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The vitality of dentin-pulp complex is fundamental to the life of tooth and is a priority for targeting clinical management strategies. Loss of the tooth, jawbone or both, due to periodontal disease, dental caries, trauma or some genetic disorders, affects not only basic mouth functions but aesthetic appearance and quality of life. One novel approach to restore tooth structure is based on biology: regenerative endodontic procedure by application of tissue engineering. Regenerative endodontics is an exciting new concept that seeks to apply the advances in tissue engineering to the regeneration of the pulp-dentin complex. The basic logic behind this approach is that patient-specific tissue-derived cell populations can be used to functionally replace integral tooth tissues. The development of such ‘test tube teeth’ requires precise regulation of the regenerative events in order to achieve proper tooth size and shape, as well as the development of new technologies to facilitate these processes. This article provides an extensive review of literature on the concept of tissue engineering and its application in endodontics, providing an insight into the new developmental approaches on the horizon. Key words:Regenerative, tissue engineering, stem cells, scaffold.

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Dental implants with the periodontium: A new approach for the restoration of missing teeth

Cited by 9 publications

References 24 publications

A comparative mechanical and bone remodelling study of all-ceramic posterior inlay and onlay fixed partial dentures

A comparative mechanical and bone remodelling study of all-ceramic posterior inlay and onlay fixed partial dentures

Dental Tissue Regeneration – A Mini-Review

From Stem to Roots: Tissue engineering in Endodontics

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