2013
DOI: 10.1177/0022034513504947
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Dental Implants Installed in Irradiated Jaws

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Cited by 97 publications
(107 citation statements)
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References 54 publications
(114 reference statements)
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“…A study suggests that irradiation negatively affects the survival of implants, as well as the difference in implant location [2, 13,14]. The maxilla compared with the mandible, the posterior jaws compared with anterior jaws and the posterior maxilla, compared with all other oral locations were associated with…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…A study suggests that irradiation negatively affects the survival of implants, as well as the difference in implant location [2, 13,14]. The maxilla compared with the mandible, the posterior jaws compared with anterior jaws and the posterior maxilla, compared with all other oral locations were associated with…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…108,109 Both animal and human studies have shown an increased risk of implant failure (up to 12 times) in irradiated patients. 110 In a recent systematic review, Chambrone et al 111 reported a mean implant survival rate ranging from 46.3 to 98% and an increased implant failure risk (RR 2.74) in irradiated patients, in particular in the maxilla (RR 5.96). Radiotherapy seems to have both early and late effects; the early effects affect mainly salivary glands, skin and oral mucosa, while the late effects involve bone changes and may lead to demineralisation, fibrosis, increased susceptibility to infection and avascular necrosis.…”
Section: Head and Neck Cancer Patientsmentioning
confidence: 99%
“…107,[112][113][114] However, two recent systematic reviews found that there is no evidence that HBOT can reduce implant failure and that better designed studies are needed to clarify the real benefit of HBOT on the survival rates of implants in irradiated jaws. 111,115 In order to increase the implant success in these patients, a few precautions have been suggested, 8,116 such as antimicrobial prophylaxis and strict surgical asepsis, and it has been recommended to wait nine months after radiotherapy before performing implant surgery. The total radiation dose should be kept under 50 Gy to reduce the risk of osseointegration failure, but in case of higher doses, the clinician may consider to use HBOT.…”
Section: Head and Neck Cancer Patientsmentioning
confidence: 99%
“…It is also reported that patients younger than 5 years of age at the start of anti-cancer treatment, who received high cranial irradiation, had a significantly increased risk of dentofacial abnormalities and especially of mandibular hypoplasia [27]. The growth repressive action of irradiation in growing children has been explained to be due to growth hormone deficiency [28]. Since radiation therapy has a growth-suppressive effect, the prognosis for treating a skeletal Class II malocclusion with growth modification or orthodontic treatment alone could be poor.…”
Section: Case Discussionmentioning
confidence: 99%