Abstract:The aim of this study was to determine the frequency and severity of dental fluorosis (DF) and the association between severity and risk factors. In a cross-sectional study, 8- to 12-year-old children, born in a Colombian district, were evaluated according to the Thylstrup and Fejerskov Index (TFI) by two calibrated examiners. Molar Incisor Hypomineralization (MIH) and dental caries (DC) were also evaluated. Ordinal logistic regression was applied p<0.05). Risk factors and lifestyle factors were collected u… Show more
“…The effect of gender on the incidence of DF has not been investigated yet. An epidemiological survey of 929 adolescents in Northern Colombia revealed that the prevalence of DF did not differ significantly between the two genders and that it had no significant effect on the incidence (Saldarriaga et al, 2021b), which is consistent with the results of another survey of 1,044 adolescents in India (Verma et al, 2017). However, notably, economically underdeveloped areas and the unequal status of different genders can cause differences in the diet and living habits of people, which may contribute to the differences in its prevalence.…”
Fluoride is commonly consider as a “double-edged sword” because low consumption of fluoride can effectively prevent dental caries, but excessive consumption of fluoride can cause fluorosis. Dental fluorosis (DF) is a characteristic feature of fluorosis in the oral cavity that is manifested as tooth color changes and evident enamel defect. Presently, the pathogenesis of DF remains unclear. Herein, we have summarized the research progress in the pathogenesis and mechanism of DF in the past 5 years.
“…The effect of gender on the incidence of DF has not been investigated yet. An epidemiological survey of 929 adolescents in Northern Colombia revealed that the prevalence of DF did not differ significantly between the two genders and that it had no significant effect on the incidence (Saldarriaga et al, 2021b), which is consistent with the results of another survey of 1,044 adolescents in India (Verma et al, 2017). However, notably, economically underdeveloped areas and the unequal status of different genders can cause differences in the diet and living habits of people, which may contribute to the differences in its prevalence.…”
Fluoride is commonly consider as a “double-edged sword” because low consumption of fluoride can effectively prevent dental caries, but excessive consumption of fluoride can cause fluorosis. Dental fluorosis (DF) is a characteristic feature of fluorosis in the oral cavity that is manifested as tooth color changes and evident enamel defect. Presently, the pathogenesis of DF remains unclear. Herein, we have summarized the research progress in the pathogenesis and mechanism of DF in the past 5 years.
“…Mixed results were observed in different studies on the gender-wise occurrence of dental fluorosis in children as discussed by Akuno et al [ 17 ]. Studies by Keçeci et al [ 18 ], Saldarriaga et al [ 19 ], and Verma et al [ 20 ] showed no relationship between gender and fluoride effect on teeth, while some other studies showed significant gender differences in the prevalence of teeth fluorosis. In the present study, more prevalence was observed in girls than in boys.…”
Background
Andhra Pradesh (AP) is one of the states in India found to have districts with endemic fluoride and YSR Kadapa district is one among them. Fluorosis is a well-known endemic disease affecting the hard tissues of the human body like teeth and bone and soft tissues like the kidneys, gastrointestinal system, nervous system, etc. Dental fluorosis is being proven as a biomarker for exposure to fluoride. This study evaluated the toxicity of fluoride in drinking water on the teeth (dental fluorosis) and on the bones (skeletal fluorosis) in YSR Kadapa district, AP.
Material and methods
A cross-sectional study was done in schools in the study areas and a total of 488 school children aged between eight to 14 years were screened for fluorosis. Consent from parents or legal representatives was taken. The information regarding personal details, source of drinking water, diet, and socio-demographic characteristics was obtained from children through a questionnaire. Oral examination of teeth was done to assess dental fluorosis by the Deans's fluorosis index and a general physical examination to assess skeletal fluorosis as per guidelines given by the Central Government of India in the National Program for Prevention of Fluorosis in India. Fluoride in drinking water samples and urine samples of school children was assessed by a fluoride ion meter. Statistical analysis was done using IBM SPSS Statistics for Windows, Version 25, (Released 2017; IBM Corp., Armonk, New York, United States). Descriptive statistics were used to assess the percentage distribution and Chi-square test of Independence for comparison between variables.
Results
The mean fluoride levels in water in the study areas ranged between 1.5mg/l to 4.2mg/l and there was a prevalence of 44.05% dental fluorosis and 0% skeletal fluorosis in the school children. A total of 48.47% of girls and 40.64% of boys were affected with dental fluorosis. A prevalence of 23.06% mild, 22.1% moderate, 5.31% very mild, and 4.55% severe dental fluorosis was observed in the examined children.
Conclusion
Our study results showed the presence of dental fluorosis with no clinical evidence of skeletal fluorosis among school children in the YSR Kadapa district of Andhra Pradesh. This indicates the fluoride toxicity on teeth in children confirming the exposure to fluoride in the YSR Kadapa district. So, further long-term follow-up surveys are necessary to evaluate skeletal fluorosis in these children though there was no clinical skeletal fluorosis. This highlights that measures need to be enforced by the local governance for the supply of defluorinated water in these areas.
“…La fluorosis dental o hipoplasia adamantina por factores ambientales o dientes moteados, es una alteración que produce discromías anormales en el esmalte dental (Saldarriaga et al, 2021). Se produce por la ingesta indiscriminada de fluoruros y por periodos prolongados, generando líneas blancas delgadas en la pieza dental hasta defectos anatómicos graves (James et al, 2021).…”
En odontología, el flúor ha permitido mermar la prevalencia de infección por caries dental, tanto en la población infantil como adulta. El objetivo fue evaluar la eficacia de los fluoruros para la prevención de caries dental, a través de su mecanismo de acción, vías de administración y efectos adversos por su aplicación indiscriminada. Se realizó un estudio de tipo revisión narrativa y se elaboraron preguntas PICO para el desarrollo de esta. La búsqueda se realizó en bases de datos como PubMed, Lilacs y el buscador Google Académico; se utilizó aplicativo web RAYYAN. El flúor es ampliamente usado en odontología, dentro de la práctica clínica se encuentran fluoruro de sodio, fluoruro estañoso y fluoruro fosfato acidulado. Este mineral se puede administrar en dos formas, sistémica y tópica; sin embargo, su uso indiscriminado puede causar fluorosis dental e intoxicaciones. Se concluye que la aplicación de flúor, aunado a políticas que promuevan la salud bucodental lograría reducir los índices de caries en las poblaciones intervenidas. Además, la capacitación constante del odontólogo permitirá incrementar el éxito en la aplicación de fluoruros, evitando efectos adversos.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.