Dental Biomaterial Scaffolds in Tooth Tissue Engineering: a Review

Hamdy, Tamer M.

doi:10.1007/s40496-023-00329-0

Cited by 8 publications

(7 citation statements)

References 50 publications

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“…This slow deterioration matches the rate at which tissue regenerates, reducing the need for intrusive removal techniques and enabling the scaffold to blend in with the body's own healing process. In dentistry applications, biodegradable scaffolds present a promising way to facilitate effective and unhindered tissue regeneration by striking a balance between scaffold degradation and tissue creation [17]. Figure 4 shows biodegradability for reduced environmental impact and bioactive molecules for enhanced tissue regeneration in regenerative dentistry.…”

Section: Biodegradabilitymentioning

confidence: 99%

The Regeneration in Dentistry with Scaffolds Application

Saberian,

Jenča,

Zafari

et al. 2024

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The Regeneration in Dentistry with Scaffolds Application" explores the dynamic interplay between scaffolds, stem cells, and growth factors in tissue engineering and regenerative dentistry. Scaffolds, resembling the extracellular matrix, serve as architectural frameworks, guiding stem cell behavior and tissue regeneration. Stem cells, with their remarkable plasticity, contribute to repair and restoration. Growth factors orchestrate cellular processes, promoting healing and tissue renewal. This comprehensive book delves into scaffold design, stem cell types, and growth factor applications, emphasizing their pivotal role in modern dental care.

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Section: Biodegradabilitymentioning

confidence: 99%

The Regeneration in Dentistry with Scaffolds Application

Saberian,

Jenča,

Zafari

et al. 2024

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“…In the presence of inflammatory conditions (i.e., acidic mediators), the QPS triggers the release of antimicrobial silver nanoparticles (AgNPs). This mechanism promotes tissue healing and reduces drug resistance [150]. In addition to loading antibiotics, researchers have also constructed the surface microstructure of hydrogels to prevent bacterial adhesion or achieve photothermal sterilization, thereby preventing infection [151][152][153].…”

Section: Hydrogels For Mandible Regenerationmentioning

confidence: 99%

Hydrogels for Oral Tissue Engineering: Challenges and Opportunities

Chen,

Deng,

Lai

et al. 2023

Molecules

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Oral health is crucial to daily life, yet many people worldwide suffer from oral diseases. With the development of oral tissue engineering, there is a growing demand for dental biomaterials. Addressing oral diseases often requires a two-fold approach: fighting bacterial infections and promoting tissue growth. Hydrogels are promising tissue engineering biomaterials that show great potential for oral tissue regeneration and drug delivery. In this review, we present a classification of hydrogels commonly used in dental research, including natural and synthetic hydrogels. Furthermore, recent applications of these hydrogels in endodontic restorations, periodontal tissues, mandibular and oral soft tissue restorations, and related clinical studies are also discussed, including various antimicrobial and tissue growth promotion strategies used in the dental applications of hydrogels. While hydrogels have been increasingly studied in oral tissue engineering, there are still some challenges that need to be addressed for satisfactory clinical outcomes. This paper summarizes the current issues in the abovementioned application areas and discusses possible future developments.

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“…Bioactive substances and nanoparticles recently incorporated into polymeric scaffolds in order to create a smart scaffold that respond to internal signals. 228 The use of regenerating biomaterials in GTR is widely established. 229 A systematic review of GTR results with a collagen membrane revealed that pocket depth reduction is predictable with or without a bone replacement.…”

Section: Clinical Applicationsmentioning

confidence: 99%

Macro, Micro, and Nano-Inspired Bioactive Polymeric Biomaterials in Therapeutic, and Regenerative Orofacial Applications

Atia,

Shalaby,

Roomi

et al. 2023

DDDT

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Introducing dental polymers has accelerated biotechnological research, advancing tissue engineering, biomaterials development, and drug delivery. Polymers have been utilized effectively in dentistry to build dentures and orthodontic equipment and are key components in the composition of numerous restorative materials. Furthermore, dental polymers have the potential to be employed for medication administration and tissue regeneration. To analyze the influence of polymer-based investigations on practical medical trials, it is required to evaluate the research undertaken in this sector. The present review aims to gather evidence on polymer applications in dental, oral, and maxillofacial reconstruction.

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Dental Biomaterial Scaffolds in Tooth Tissue Engineering: a Review

Cited by 8 publications

References 50 publications

The Regeneration in Dentistry with Scaffolds Application

The Regeneration in Dentistry with Scaffolds Application

Hydrogels for Oral Tissue Engineering: Challenges and Opportunities

Macro, Micro, and Nano-Inspired Bioactive Polymeric Biomaterials in Therapeutic, and Regenerative Orofacial Applications

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