Dental and periodontal health status of subjects with sickle cell disease

Abstract

Background/purpose: Sickle cell disease (SCD) is a chronic, hereditary, autosomal recessive disorder. The pathophysiology of SCD is thought to result from polymerization of hemoglobin S in red blood cells under hypoxic conditions, which results in vaso-occlusion. The aim of this study was to determine the periodontal and dental health status of patients with SCD. Materials and methods: Fifty-five SCD patients and 41 healthy individuals were evaluated. Detailed medical and dental histories were taken, and a record made of dental status (missing teeth, restorations, impacted teeth, root canal treatment), periodontal status [plaque index (PI), gingival index (GI), probing depth (PD), bleeding on probing (BOP)], alveolar bone level (ABL), mandibular cortex index, and bone quality index. Results: Two hundred and six teeth were missing, and a total of 195 teeth had restorations. Between-group differences existed for the PI, GI, and BOP; these variables were higher in patients than in the healthy individuals (P < 0.0001). No between-group differences existed for PD. In patients, there was a positive correlation between PD and BOP (P < 0.0001; r Z 0.657), PD and GI (P Z 0.02; r Z 0.299), PD and PI (P Z 0.01; r Z 0.343); BOP and GI (P < 0.0001; r Z 0.503), BOP and PI (P < 0.0001; r Z 0.496); and GI and PI (P Z 0.003; r Z 0.388). The ABL in patients was found to be similar to that of the general population with an unknown periodontal condition.

Are sickle cell anaemia and sickle cell trait predictive factors for periodontal disease? A cohort study

“…Our results indicated no correlation between SCA and periodontal diseases, a finding already observed in the majority of previous studies . It has been reported that inflammatory conditions and severity of periodontal diseases in individuals with SCA seem to be correlated with oral hygiene conditions but not with the haematological disorder .…”

Oral Health Status and Impact on Oral Health-Related Quality of Life in Children with Thalassemia Major

“…Patients preoccupied with their major life threatening condition, therefore neglecting a basic preventive dental care. 11 Another reason could be because of the increased sensitivity to local factors (oral hygiene, tooth brushing habit and frequency of sugar intake). 12 The present study also showed that prevalence of dental caries was significantly higher in thalassemia patients than in age matched healthy controls, suggesting a need for restorative dental care in thalassemia children.…”

Detección precoz de anemia de células falciformes por medio de un diagnóstico clínico y radiográfico oral. Reporte de caso / Early Detection of Sickle Cell Anemia by oral Diagnosis and oral Radiographs. Case Report

“…En cuanto a los hallazgos clínicos orales, aunque muchos autores no reconocen la condición periodontal como un factor predisponente de ACF (33,34), se puede generar una asociación entre las dos enfermedades cuando se relacionan con otros signos clínicos orales (35). Clínicamente, la paciente del caso reportado y sus hermanos presentaron surcos periodontales activos, palidez palatal y sangrado gingival al cepillado, este último fue el motivo de consulta.…”