Dental and oral manifestations of celiac disease

Abstract

BackgroundThe objective of this study was to evaluate the dental and oral manifestations in patients with celiac disease.Material and MethodsThe sample consisted of 40 patients with the disease and 40 without the disease matched by age in southern Brazil. The CD group included patients previously diagnosed by positive anti-endomysial (IgA) examination and confirmed by small intestine biopsy. The presence of dental enamel defects and dental caries was evaluated by a calibrated researcher according to AINE’s and WHO’s criteria, respectively. The history of recurrent aphthous ulcers and dry mouth was obtained through reporting. For the evaluation of the salivary flow, the saliva samples were obtained through the non-stimulated and stimulated saliva collection method.Results There was a significant association between CD and dental enamel defects (OR=2.38, P=0.045) and dry mouth (OR=9.15, P=0.002). No difference was found for the report of recurrent aphthous ulcers and caries experience between the two groups. Patients with CD had normal pattern of unstimulated and stimulated saliva flow rates (0.67 ± 0.38 ml / min and 1.14 ± 0.47 ml / min, respectively). A higher occurrence of dental enamel defects was observed in patients with classic CD (P=0.054). Of the 1,962 permanent teeth, 59 presented dental enamel defects, 71.8% of which were in patients with CD (P=0.001), predominantly in molars (P=0.009).ConclusionsCD increased the likelihood of dental enamel defects and dry mouth sensation. The oral examination can be an important auxiliary tool for the identification of cases of the disease. Key words:Celiac disease, oral manifestations, dental enamel hypoplasia.

Caries among adult patients with controlled celiac disease: A cross‐sectional study

“…Dental enamel defects and aphthous ulcers are the most common and well documented oral manifestations, and several studies have confirmed the occurrence of these lesions in both children and adults with CD 8,9,11,13‐19 . To the contrary, the association between caries experience and salivary gland dysfunction and CD continues to be controversial 16‐18 . To our knowledge, this is the first study that investigated caries experiences and salivary parameters among adults with celiac disease.…”

“…These include dental enamel defects, aphthous stomatitis, angular cheilitis, dry mouth, and dental caries 13‐18 . Dental enamel defects and aphthous ulcers are the most common and well documented oral manifestations, and several studies have confirmed the occurrence of these lesions in both children and adults with CD 8,9,11,13‐19 . To the contrary, the association between caries experience and salivary gland dysfunction and CD continues to be controversial 16‐18 .…”

Dental maturity in children with celiac disease: a case–control study

“…However, the prevalence of delayed DM in our study varied from those studies in that DA was assessed clinically, by counting the number of erupted teeth [ 9 , 22 – 24 ], with a range from 20 to 38% in children with CD. Greater prevalence of delayed DE has likewise been reported in CD patients than controls [ 8 ], and was considered a significant oral manifestation of CD in the appraisals of several studies [ 23 , 25 , 26 ].…”

Evaluation of Dental Health in Terminally Ill Patients

“…Our findings were in concordance with the results of Cruz et al, who found that a higher occurrence of dental enamel defects was observed in patients with celiac disease (71.8%), predominantly in molars. Enamel hypoplasia may be associated with hypocalcemia, genetic susceptibility, or an autoimmune reaction in the enamel during odontogenesis [ 38 ].…”