DENTAL ABNORMALITIES OF EIGHT WILD QINLING GIANT PANDAS (<i>AILUROPODA MELANOLEUCA QINLINGENSIS</i>), SHAANXI PROVINCE, CHINA

Jin, Yipeng; Chen, Si; Chao, Yanqiao; Pu, Tianchun; Xu, Hongqian; Liu, Xiaobin; Zhao, Kaihui; Nie, Yonggang; Wei, Wei; Lin, Dazhen

doi:10.7589/2014-12-289

Cited by 15 publications

(13 citation statements)

References 18 publications

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“…material). Although we have not found carious lesions in the bamboo-feeder giant panda ( A. melanoleuca ), they can exist in captive specimens 22 . Despite this, the giant panda has a low incidence of dental caries that could reflect the low degree of sugars that contained in the bamboo stems 23 or the high-resistance of crenulated enamel 24 .…”

Section: Discussioncontrasting

confidence: 73%

Dental caries in the fossil record: a window to the evolution of dietary plasticity in an extinct bear

Figueirido

Pérez‐Ramos

Schubert

et al. 2017

Sci Rep

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During the late Pleistocene of North America (≈36,000 to 10,000 years ago), saber-toothed cats, American lions, dire wolves, and coyotes competed for prey resources at Rancho La Brea (RLB). Despite the fact that the giant short-faced bear (Arctodus simus) was the largest land carnivoran present in the fauna, there is no evidence that it competed with these other carnivores for prey at the site. Here, for the first time, we report carious lesions preserved in specimens of A. simus, recovered from RLB. Our results suggest that the population of A. simus from RLB was more omnivorous than the highly carnivorous populations from the Northwest. This dietary variation may be a consequence of different competitive pressures.

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Section: Discussioncontrasting

confidence: 73%

Dental caries in the fossil record: a window to the evolution of dietary plasticity in an extinct bear

Figueirido

Pérez‐Ramos

Schubert

et al. 2017

Sci Rep

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“…Ageing mammals in captivity often develop cataracts due to the accumulation of oxidative damage [ 1 ]. This has been observed in captive giant pandas, which typically live up to 10 years longer than their wild counterparts [ 5 , 6 ]. The prevalence of cataracts in the current population of aged giant pandas is ~ 20% and this is associated with a declining quality of life, as the animals find it difficult to feed and negotiate their surroundings.…”

Section: Discussionmentioning

confidence: 95%

“…Cataracts are the main cause of blindness in ageing humans and other primates, as well as companion animals such as dogs and cats [ 2 – 4 ]. They are also prevalent in captive giant pandas ( Ailuropoda melanoleuca ), which live to 15–20 years in the wild but 25–30 years in captivity [ 5 , 6 ]. Giant pandas 18 or more years old are described as aged because they have reached an equivalent human age of ~ 75.…”

Section: Introductionmentioning

confidence: 99%

RNA-Seq analysis in giant pandas reveals the differential expression of multiple genes involved in cataract formation

You¹,

Bai²,

Li³

et al. 2021

BMC Genom Data

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Background The giant panda (Ailuropoda melanoleuca) is an endangered mammalian species native to China. Fewer than 2500 giant pandas are known to exist, many of which are bred in captivity as a means to preserve and repopulate the species. Like other captive mammals, giant pandas acquire age-related cataracts, reducing their quality of life. Recent comparative genome-wide methylation analysis revealed 110 differentially methylated genes associated with cataract formation including six also associated with the formation of age-related cataracts in humans. Results To investigate the pathological pathway in greater detail, here we used RNA-Seq analysis to investigate the differential expression profiles of genes in three giant pandas with cataracts and three healthy controls. We identified more than 700 differentially expressed genes, 29 of which were selected for further analysis based on their low q-value. We found that many of the genes encoded regulatory and signaling proteins associated with the control of cell growth, migration, differentiation and apoptosis, supporting previous research indicating a key role for apoptosis in cataract formation. Conclusion The identification of genes involved in the formation of age-related cataracts could facilitate the development of predictive markers, preventative measures and even new therapies to improve the life of captive animals.

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“…It is well known that this result is much more difficult to obtain in diabetic patients, due both to the decrease in reactivity of neutrophils and leukocytes and the presence of peripheral vasculopathy. A persistence of bacteria within the pocket or on root surfaces seems to undermine healing, since the presence of residual antigenic material on the root surface could result in an increase in the number of neutrophils at the initial healing stage and hence a greater release of proteolitic enzymes, which could in turn delay clot maturation (25)(26)(27)(28)(29)(30). Periodontal diseases have certainly an impact on this situation (20,23,24,.…”

Section: Discussionmentioning

confidence: 99%

Effects of the Application of High-Pressure Oxygen on the Treatment of Periodontal Disease in Diabetic Patients

Sabatini

Ricci²,

Candotto

et al. 2017

ORL

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SUMMARYPurpose. In this study we wanted to observe the improvement in the healing of periodontal tissues in a group of diabetic patients treated with traditional methods compared to another group treated with the addition of oxygen. The potential of oxygen has long been known in the field of plastic surgery, where it is used to treat burns and skin lesions. Materials and methods. This study consists in a split mouth study which involved 30 patients. We carefully treated them with periodontal therapy using manual and mechanical instrumentation. Then, we applied oxygen in half mouth according to randomization list. Finally we checked up patients after some weeks. Results. Our results highlight that all areas treated with oxygen application healed more rapidly and better than no treated areas. Conclusions. All in all, we have demonstrated that oxygen can improve the outcome of non-surgical periodontal treatment in diabetic subjects.

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DENTAL ABNORMALITIES OF EIGHT WILD QINLING GIANT PANDAS (AILUROPODA MELANOLEUCA QINLINGENSIS), SHAANXI PROVINCE, CHINA

Cited by 15 publications

References 18 publications

Dental caries in the fossil record: a window to the evolution of dietary plasticity in an extinct bear

Dental caries in the fossil record: a window to the evolution of dietary plasticity in an extinct bear

RNA-Seq analysis in giant pandas reveals the differential expression of multiple genes involved in cataract formation

Effects of the Application of High-Pressure Oxygen on the Treatment of Periodontal Disease in Diabetic Patients

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