Densitas tulang mandibula pengguna obat anti hipertensi calcium  channel blocker (CCB) melalui radiograf panoramik

Gunawan, Gunawan; Sitam, Suhardjo; Epsilawati, Lusi

doi:10.32793/jrdi.v4i2.527

Cited by 4 publications

(7 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…27 A research in Wistar rats given am insignificant changes in bone, 18 other stated amlodipine impairs the bone marrow mo antihypertensive drug therapy, there can be an alteration of bone quality due to the disruption of calcium metabolism. 1,8,17,18,20,21,23,24 However, the effects of amlodipine on calcium metabolism and bone density themselves are still debated. There have been many studies that examined the relationship between these two and some of them concluded that the relationship is inconsistent and contradictory, including the result of this study.…”

Section: Ionmentioning

confidence: 99%

Comparison of panoramic mandibular cortical bone quality indexes in amlodipine users and healthy individuals

Nurrachman

Epsilawati²,

Azhari³

et al. 2022

Majalah Kedokteran Gigi Indonesia

View full text Add to dashboard Cite

Hypertension and osteoporosis are believed to be linked to to each other. Previous studies have suggested that the imbalance of calcium metabolism in hypertensive condition and the use of calcium channel blockers such as amlodipine may lower the density and quality of bone. Panoramic radiography has been widely used as a reliable tool in assessing bone quality. One indicator of bone quality in panoramic radiograph is the macrostructure evaluation of mandibular cortical bone by using various indexes such as mandibular cortical index (MCI) and antegonial index (AI). This research aimed to compare the bone quality of hypertensive patients with amlodipine and healthy individuals using MCI and AI. In this study we used sixty panoramic radiographs of hypertensive patients with amlodipine and healthy individuals, thirty for each group, with various aspects of demography. The MCI analysis was done by dividing the mandibular cortical shape into three different qualitative categories and the AI analysis was done quantitatively by measuring the width of mandibular cortical bone in antegonial region using ImageJ software. There were statistically significant differences in the results between the two groups in terms of both AI (p = 0.000) and MCI (p = 0.001) in which hypertensive group had lower score. Based on this research, there were differences of mandibular bone quality of hypertensive patients with amlodipine and healthy individuals, particularly in its macrostructure.

show abstract

Section: Ionmentioning

confidence: 99%

Comparison of panoramic mandibular cortical bone quality indexes in amlodipine users and healthy individuals

Nurrachman

Epsilawati²,

Azhari³

et al. 2022

Majalah Kedokteran Gigi Indonesia

View full text Add to dashboard Cite

show abstract

“…Panoramic radiograph is a routine examination in dentistry that could use to assess changes quality of bone density. 16 The criteria for elderly according to the Ministry of Health of the Republic of Indonesia are over 50 years of age including early age (50 -64 years) and over 65 years. 17 The WHO meeting in Africa at the Harare MDS Workshop in 2000 decided that the chronological age that is said to be old age is 60 years, and in 2001 it was revised to 50 years considering the different conditions in each country.…”

Section: Discussionmentioning

confidence: 99%

Analysis of the panoramic radiographic density of the mandibular bone in the elderly due to increased cortisol levels

Rachmawati

Firman

Epsilawati

et al. 2022

JRDI

Self Cite

View full text Add to dashboard Cite

Objectives: Mandibular bone is generally formed by intramembranous ossification. Bone density mandible can be assessed from the trabecular pattern. In the elderly, the hormone cortisol affects bone formation through bone resorption by blocking calcium. The purpose of this study was to determine the correlation of cortisol levels to mandibular bone density in elderly women and men. Materials and Methods: This study was an analytic survey, where the population was determined from secondary patient data in the form of 31 panoramic radiographs and 31 laboratory results of cortisol examination, the research sample was divided into two groups. The bone density of the mandible was assessed from the trabeculae of the neck condyles region of the right and left. Density assessment using the ImageJ software program on panoramic radiographs was an examination that is often done in dentistry. Results: This study showed that the lowest density was in the group of women over 60 years. The results of the t-test with the independent sample obtained a p-value of > 0.05, which indicated there is no significant difference. The negative correlation value indicated that the relationship that occurs is opposite, p-value <0.05 which indicated the lower bone density, the higher cortisol level. Conclusion: Based on the results of the study, there was a correlation that with the increasing age of both women and men there was an increase in cortisol levels and a decrease in mandibular density.

show abstract

“…9 Hypertensive patients who consume antihypertensive medication such as amlodipine will affect their calcium levels, which subsequently impacts their bone condition and becomes a risk factor for bone fractures. 10 Amlodipine can also decrease bone quality by reducing the production of steroid hormones, thus reducing bone formation and decreasing the volume of trabecular and cortical bone in the mandible. 11 Panoramic radiography is one of the dental medicine techniques that can provide an image encompassing the teeth, maxilla, and mandible, allowing visualization of the inferior mandibular cortex.…”

mentioning

confidence: 99%

“…The examination of panoramic radiography is conducted using several qualitative and quantitative indices, namely mandibular cortical index (MCI), mental index (MI), panoramic mandibular index (PMI), and gonion antegonial index. 10,12 PMI is an index that provides results in the form of a comparison between the thickness of the mandibular cortex and the distance from the inferior mental foramen to the inferior border of the mandibular cortex. Therefore, this measurement method allows calculations to be performed despite variations in magnification by different researchers.…”

mentioning

confidence: 99%

Differences in Panoramic Mandibular Index value between male and female hypertension patients using panoramic radiography

Lestari,

Sarifah,

Aspriyanto

et al. 2023

JRDI

View full text Add to dashboard Cite

Objectives: This study is aimed to analyze the panoramic mandibular index value in male and female hypertensive patients using panoramic radiography. Materials and Methods: This research is a comparative analytic research with a purposive sampling technique. The study sample was hypertensive patients at Ulin Hospital, Banjarmasin from March to May 2023. Results: The results showed that there was no statistically significant difference through statistical data on the panoramic mandibular index value between men (0.27 ± 0.07) and women (0.26 ± 0.09), The age group that experienced a decrease in mandibular cortical thickness was most in the age group ≥ 65 years (0.22 ± 0.06). Conclusion: It is known that there is no significant difference in the panoramic mandibular index value between women and men.

show abstract

Densitas tulang mandibula pengguna obat anti hipertensi calcium channel blocker (CCB) melalui radiograf panoramik

Cited by 4 publications

References 12 publications

Comparison of panoramic mandibular cortical bone quality indexes in amlodipine users and healthy individuals

Comparison of panoramic mandibular cortical bone quality indexes in amlodipine users and healthy individuals

Analysis of the panoramic radiographic density of the mandibular bone in the elderly due to increased cortisol levels

Differences in Panoramic Mandibular Index value between male and female hypertension patients using panoramic radiography

Contact Info

Product

Resources

About