2018
DOI: 10.3390/sym10040087
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Dense Fully Convolutional Segmentation of the Optic Disc and Cup in Colour Fundus for Glaucoma Diagnosis

Abstract: Glaucoma is a group of eye diseases which can cause vision loss by damaging the optic nerve. Early glaucoma detection is key to preventing vision loss yet there is a lack of noticeable early symptoms. Colour fundus photography allows the optic disc (OD) to be examined to diagnose glaucoma. Typically, this is done by measuring the vertical cup-to-disc ratio (CDR); however, glaucoma is characterised by thinning of the rim asymmetrically in the inferior-superior-temporal-nasal regions in increasing order. Automat… Show more

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Cited by 137 publications
(95 citation statements)
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“…The recurrent block increases the network depth while keeping the number of adjustable parameters unchanged through weight sharing. This is consistent with the purpose of the current CNN architecture [5][6][7]: Using relatively few parameters for more in-depth research. At the same time, we further explored the PLOS ONE spatial pyramid model and applied it to RFC-Net.…”
Section: Introductionsupporting
confidence: 79%
“…The recurrent block increases the network depth while keeping the number of adjustable parameters unchanged through weight sharing. This is consistent with the purpose of the current CNN architecture [5][6][7]: Using relatively few parameters for more in-depth research. At the same time, we further explored the PLOS ONE spatial pyramid model and applied it to RFC-Net.…”
Section: Introductionsupporting
confidence: 79%
“…Current literature in OD/OC segmentation make use of classical overlap metrics such as the intersectionover-union (IoU, also known as Jaccard index) (Al-Bander et al, 2018;Edupuganti et al, 2018;Fu et al, 2018;Lim et al, 2015;Sevastopolsky, 2017;Sevastopolsky et al, 2018;Sun et al, 2018;Zilly et al, 2015) and the Dice index (Al-Bander et al, 2018;Edupuganti et al, 2018;Sevastopolsky, 2017;Sevastopolsky et al, 2018;Sun et al, 2018;Zilly et al, 2015). Although different by definition, these two metrics can be computed from each other, as they are defined as ratios of overlap between the predicted area and the manual reference annotation (Taha and Hanbury, 2015).…”
Section: Metricsmentioning
confidence: 99%
“…The FCN is the first DL-based image segmentation method. Its merit lies in the realization of end-to-end segmentation [19,20]. However, the details of FCN image segmentation are not good enough, for failing to consider the spatial correlation between pixels.…”
Section: Structure Of U-net Modelmentioning
confidence: 99%