Dengue virus infection outbreak: comparison with other viral infection outbreak

Chaudhry, Mohammad Rauf A

doi:10.1016/b978-0-12-818270-3.00003-5

Cited by 4 publications

(3 citation statements)

References 18 publications

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“…A higher value of

, greater than 1, indicates that the pathogen continues to spread if there is no environmental change or external intervention [ 48 ]. This measure is essential for disease control and mitigation effort [ 49 ]. Estimation of

is conducted in different countries [ 50 , 51 , 52 ].…”

Section: Results and Interpretationmentioning

confidence: 99%

Modeling COVID-19 Transmission Dynamics: A Bibliometric Review

Goswami

Labib

2022

IJERPH

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A good amount of research has evolved just in three years in COVID-19 transmission, mortality, vaccination, and some socioeconomic studies. A few bibliometric reviews have already been performed in the literature, especially on the broad theme of COVID-19, without any particular area such as transmission, mortality, or vaccination. This paper fills this gap by conducting a bibliometric review on COVID-19 transmission as the first of its kind. The main aim of this study is to conduct a bibliometric review of the literature in the area of COVID-19 transmission dynamics. We have conducted bibliometric analysis using descriptive and network analysis methods to review the literature in this area using RStudio, Openrefine, VOSviewer, and Tableau. We reviewed 1103 articles published in 2020–2022. The result identified the top authors, top disciplines, research patterns, and hotspots and gave us clear directions for classifying research topics in this area. New research areas are rapidly emerging in this area, which needs constant observation by researchers to combat this global epidemic.

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“…A higher value of

is conducted in different countries [ 50 , 51 , 52 ].…”

Section: Results and Interpretationmentioning

confidence: 99%

Modeling COVID-19 Transmission Dynamics: A Bibliometric Review

Goswami

Labib

2022

IJERPH

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“…Transmission, on the other hand, is usually considered as a proxy of viral fitness, because it is related to its basic reproductive number, reflecting the ability of the virus to replicate, persist and spread within hosts and in the population [44][45][46][47]. Therefore, we estimated the transmission of each haplotype by interrogating worldwide SARS-CoV-2 sequence data.…”

Section: Favoured and Forbidden Mixtures Of Ntd Marker Combinations I...mentioning

confidence: 99%

Adaptive advantage of deletion repair in the N-terminal domain of the SARS-CoV-2 spike protein in variants of concern

Álvarez-Herrera,

Ruiz-Rodriguez,

Navarro-Domínguez

et al. 2024

Preprint

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Mutations within the N-terminal domain (NTD) of the spike (S) protein play a pivotal role in the emergence of successful SARS-CoV-2 viral lineages. This study investigates the influence of novel combinations of NTD lineage-defining mutations found in the Alpha, Delta, and Omicron variants on viral success. We performed comparative genomics of more than 10 million public SARS-CoV-2 samples to decipher the transmission success of different NTD markers. Additionally, we characterized the viral phenotype of such markers in a surrogate in vitro system. We found that viruses bearing repaired deletions SDeltaH69/V70 and SDeltaY144 in Alpha background were associated with increased transmission rates. After the emergence of the Omicron BA.1 lineage, Alpha viruses harbouring both repaired deletions still showed increased transmission compared to their BA.1 counterparts. Remarkably, Alpha viruses with the SDeltaH69/V70 repair displayed the highest emergence rate, while those in BA.1 exhibited the lowest. Moreover, repaired deletions were more frequently observed among older individuals infected with Alpha, but not with BA.1. In vitro biological characterization of Omicron BA.1 spike deletion repair patterns revealed substantial differences with Alpha. In BA.1, SDeltaV143/Y145 repair enhanced fusogenicity and susceptibility to neutralization by vaccinated individuals' sera. In contrast, the SDeltaH69/V70 repair did not significantly alter these traits but reduced viral infectivity. Simultaneous repair of both deletions led to lower fusogenicity. These findings highlight the intricate genotype-phenotype landscape of the spike NTD in SARS-CoV-2, which impacts viral biology, transmission efficiency, and susceptibility to neutralization. Overall, this study advances our comprehension of SARS-CoV-2 evolution, carrying implications for public health and future research.

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“…Hence, there is a necessity to develop an efficient way to control its population and the spread of the disease. Besides, several other causes such as increased urbanization, ecological changes, migration of people, exchange of goods, and biological contests (e.g., development of resistance for virus) stimulate the spread of disease to new regions ( Chaudhry 2019 ).…”

Section: Epidemiology Of Denguementioning

confidence: 99%

Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review

et al. 2022

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Dengue has become a worldwide affliction despite incessant efforts to search for a cure for this long-lived disease. Optimistic consequences for dengue vaccine are implausible as the efficiency is tied to previous dengue virus (DENV) exposure and a very high cost is required for large-scale production of vaccine. Medicinal plants are idyllic substitutes to fight DENV infection since they constitute important components of traditional medicine and show antiviral properties, although the mechanism behind the action of bioactive compounds to obstruct viral replication is less explored and yet to be discovered. This review includes the existing traditional knowledge on how DENV infects and multiplies in the host cells, conscripting different medicinal plants that obtained bioactive compounds with anti-dengue properties, and the probable mechanism on how bioactive compounds modulate the host immune system during DENV infection. Moreover, different plant species having such bioactive compounds reported for anti-DENV efficiency should be validated scientifically via different in vitro and in vivo studies.

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Dengue virus infection outbreak: comparison with other viral infection outbreak

Cited by 4 publications

References 18 publications

Modeling COVID-19 Transmission Dynamics: A Bibliometric Review

Modeling COVID-19 Transmission Dynamics: A Bibliometric Review

Adaptive advantage of deletion repair in the N-terminal domain of the SARS-CoV-2 spike protein in variants of concern

Traditional Knowledge to Contemporary Medication in the Treatment of Infectious Disease Dengue: A Review

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