Dengue vaccine acceptance and willingness to pay

Abstract

The introduction of new vaccines is accompanied by a variety of challenges. Among these, very important ones concern the questions whether the public is willing to accept and willing to purchase the vaccine. Here we discuss factors associated with these questions in the context of vaccines that are becoming available against dengue virus infection. We reviewed published studies available from PubMed and Embase, conducting a meta-analysis when possible and narrative review when the data did not qualify for meta-analysis. We found that attitude toward vaccination and socioeconomic level had significant associations with dengue vaccine acceptance. In addition, socioeconomic level, knowledge, attitude and practice regarding dengue fever, having personally experienced dengue fever and vaccine price were associated with willingness to pay for dengue vaccine. To improve acceptance and willingness to pay for dengue vaccine, well-designed introduction programs that address the associated factors in a contextspecific manner are essential.

Consumer willingness to pay for a hypothetical Zika vaccine in Brazil and the implications

“…According to Harapan et al, factors such as the socioeconomic level, knowledge, attitude and practice regarding dengue fever, and having personally experienced dengue fever, are associated with a greater willingness to pay for a dengue vaccine [25]. However in our study, respondents who had zika infection did not demonstrate a higher value of the willingness to pay compared with those who never had this flaviviruse.…”

Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades

“…Because of the unprecedented complexity and varying efficacy, the use of this vaccine is recommended only for populations with dengue seroprevalence rates above 80% or to seropositive individuals after screening test . Several studies also have assessed the feasibility and complexity of dengue vaccination within an Indonesian context . Currently, there are no vaccine recommendations that have been released for travellers from nonendemic to endemic countries such as Indonesia …”

Socioeconomic and Attitudinal Variables Associated with Acceptance and Willingness to Pay Towards Dengue Vaccine: A Systematic Review

“…We reviewed several factors associated with dengue vaccine acceptance. Until now (updated-January 2, 2017), only two studies (11,12) evaluated factors associated with dengue vaccine acceptance. Although there were several factors associated with vaccine acceptance from individual study (attitude towards vaccination, preventive measures against dengue, attitude towards dengue, knowledge on dengue fever, socioeconomic level, and dengue experience), our meta-analysis revealed that only attitude towards vaccination and socioeconomic level had significant associations with dengue vaccine acceptance.…”

“…In vaccination programs, a new vaccine has the potential to bring a variety of problems. The problem of dengue vaccine that is categorized as a new vaccine is whether the public will accept and be willing to purchase the vaccine (11) and willingness to pay (WTP).…”