Dengue hemorrhagic fever complicated by pancreatitis

Fontal, Guido Ricardo Gonzalez; Henao-Martínez, Andrés F

doi:10.1590/s1413-86702011000500015

Cited by 8 publications

(4 citation statements)

References 5 publications

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“…The exact mechanism with which dengue virus leads to acute pancreatitis is unclear; however, multiple postulates have been put forward. 12 , 14 Direct invasion of pancreas by virus leading to inflammation and destruction of pancreatic acinar cells is a commonly postulated mechanism. Another possible mechanism is through an autoimmune process against pancreatic islet cells, causing edema of ampulla of Vater with subsequent obstruction to the pancreatic outflow.…”

Section: Discussionmentioning

confidence: 99%

Dengue fever presenting with acute pancreatitis: A case report

Kashyap,

Dhamala,

Dahal

et al. 2024

SAGE Open Medical Case Reports

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Acute pancreatitis is an acute inflammation of the pancreas, with subsequent involvement of surrounding tissues and organ systems. Viral etiology of acute pancreatitis is uncommon; however, multiple viruses have been implicated. Dengue virus has also been found responsible for acute pancreatitis, with possible etiologies linked to direct viral invasion, autoimmune mechanism, or as a complication of dengue shock syndrome. We present a case of a 24-year-old female who presented with epigastric pain and vomiting in the background of a febrile illness and was later diagnosed with mild acute pancreatitis complicating dengue fever.

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Section: Discussionmentioning

confidence: 99%

Dengue fever presenting with acute pancreatitis: A case report

Kashyap,

Dhamala,

Dahal

et al. 2024

SAGE Open Medical Case Reports

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“…Our patient also had severe dengue which was complicated by acute pancreatitis which was evident by raised serum amylase and lipase and ultrasound findings. Hyperlipasemia and enlarged pancreas have been known to occur in DF; but acute pancreatitis is an atypical and rare presentation [27][28][29]. The exact pathogenesis of pancreatic involvement in dengue is not known.…”

Section: Discussionmentioning

confidence: 99%

Expanded Dengue Syndrome Presenting as Acute Pancreatitis

Gomes¹

2021

CMRR

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Dengue is a painful, debilitating mosquito-borne disease(female mosquitoes of the Aedes genus, principally Aedes aegypti)caused by any one of four closely related dengue viruses.It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever(with or without shock). Expanded dengue syndrome (EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystemic and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system. Here we present a case of 35 years old female without any comorbidities who was serologically diagnosed with dengue developed severe upper abdominal pain on 2ndafebrile day and eventually diagnosed as acute pancreatitis both by raised serum lipase and ultrasonographic evidence of swollen pancreas. She was treated conservatively and improved. Thus, all clinicians should keep in mind the possibility of acute pancreatitis as a part of expanded dengue syndrome.

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“…There were few case reports published on adults with similar clinical course (8,10,11) . One patient had acute pancreatitis as an atypical manifestation of dengue infection leading to transient diabetes.…”

Section: Discussionmentioning

confidence: 99%