Dengue Fever

Abstract

Objectives: To determine the frequency and characteristics of dengue patients.Study Design: Cross sectional observational study. Setting: Qazi Hussain Ahmed MedicalComplex Nowshera. Period: 5th July to 25th Sept 2017. Material and Methods: A total of72 cases were received for dengue serology. Relevant information’s were collected on a predesignedquestionnaire prepared in accordance with the objectives of the study. Results: Atotal of 117 patients were referred from fever clinic and emergency OPD for dengue serology.72(61.5%) were males and 45(38.5%) were females. 24(20.5%) cases were dengue positive.14(12%) were NSL1 positive, 8(8.8%) were IgM positive and 2 (1.7%) were IgM&IgG positive.We received patient in the range of 4 years to 60 years, Mean with SD was 27 +3 years. Out of14 NSL1 positive cases 8 were males and 6 females. 2 females were IgG positive. The spectrumof dengue in correlation with gender was significantly positive with p value .026. In two casesplatelet at first visit were 58000/cmm3 that were both IgM&IgG positive. Out of 24 positivedengue cases two cases were also positive for plasmodium vivax (ring tropozoites). 6 caseswere managed in hospital and discharged home with an average stay of 3 days and 4 casesreferred to Lady Reading Hospital Peshawar for repeated platelet transfusion. Mortality waszero in our cases. Conclusion: The suspicion rate of the clinician for dengue from fever clinicwas 1:7. The cause of poor rate can be contributed to the patient insist for doing the denguetest before they are screened for MP and FBC etc. NSL1 was positive in 6 cases that showsthat people reach the health care facility for screening well in time and patient are educatedabout the dengue. Females 50% positive cases were IGM and IGG positive that shows femalereceive the health care later than males as NSL1 positivity in female gender is less than males.The spectrum of dengue in correlation with gender was significantly positive with p value .025that shows mosquito has some affinity for specific gender, or dengue virus has it for differencein gender or the inside immunity of the both gender is involved that causes different mode ofpresentation and activation of antibodies.

Burden and distribution of dengue infection in Pakistan (2000-19): a review

“…The minimum number of cases (N=38) were reported from KP (Usman et al, 2011) while the maximum number of cases (N=3342) were reported from Sindh during decade I (Khan et al, 2007(Khan et al, , 2008Hasan et al, 2013, Ahmed et al, 2008Riaz et al, 2009;Shamim, 2010;Wasay et al, 2008a, b;Khalil et al, 2014;Baqi et al, 2010;Ali et al, 2011;Jahan et al, 2011). Of all the cases from KP, high number of cases (N=22740) were reported from district Swat during 2013 which are 48.6% of the total dengue cases reported from the province (Ali et al, 2016;Khan and Khan, 2015;Chaudhry et al, 2017;Lutfullah et al, 2017;Suleman et al, 2016;Khan et al, 2017a;Khan, 2018;Khan and Bari, 2018). Similarly, 58.5% (4475/7649) of the total cases reported from Punjab were from the capital city Lahore only during 2011 (Iqtadar et al, 2017b;Khan et al, 2013a, b;Ahmed et al, 2013;Rashid et al, 2012;Mahmood et al, 2013;Saqib et al, 2014a, b;Asghar and Farooq, 2011;Idrees et al, 2012;Raza et al, 2017;Naeem et al, 2018;Assir et al, 2014a, b;Sheikh et al, 2012;Chaudhry et al, 2018).…”