Dengue: A Silent Killer, a Worldwide Threat

Sakinah, Siti; Kumaran, Sharmilah Kumari; Mok, Pooi Ling; Higuchi, Akon; Benelli, Giovanni; Kumar, Suresh

doi:10.1007/978-3-319-94075-5_4

Cited by 3 publications

(1 citation statement)

References 91 publications

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“…Therefore, a fast and selective diagnosis of the viral infection is needed to control and treat the disease. MIPs are the artificial receptors for the detection of emerging virus infections compatible with natural antibodies due to their high sensitivity, selectivity, portability, low cost [28,29]. In this review, we shall focus on the surrounding literature related to the recognition of human viral pathogens by utilizing the MIPs.…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymers: Promising Tool for the Human Virus Detection

Khan

Asif

Khatoon³

et al. 2021

Pak J Anal Environ Chem

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Molecular imprinting is an attractive research area for synthesizing unique functional polymers with high selectivity due to template oriented active sites. Molecularly imprinted polymers (MIPs) have a wide range of applications in chemical and biological sensing, drug delivery, and solidphase extraction owing to mechanical stability, reversibility, reproducibility, and cross-validity. MIPs are compatible with natural antibodies and are being used as antibody mimics/receptors in the biomedical field. Today, viral detection is the most popular research area due to emerging viral diseases with genetic variability and drug resistance. Therefore, there is a need to control viral infections by discriminative recognition of the viral pathogens. This review summarizes the literature on the detection of human viruses by using MIPs.

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Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymers: Promising Tool for the Human Virus Detection

Khan

Asif

Khatoon³

et al. 2021

Pak J Anal Environ Chem

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Pathogenicity and Transgenerational Effects of Metarhizium anisopliae on the Demographic Parameters of Aedes albopictus (Culicidae: Diptera)

Shoukat

Hassan

Shakeel

et al. 2019

Journal of Medical Entomology

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Dengue fever is a vector-borne infectious disease that spreads swiftly and threatens human lives in several tropical countries. Most of the strategies employed for the control of Aedes albopictus (Skuse) involve synthetic chemicals. The indiscriminate use of synthetic chemicals has led to the development of resistance and is unsafe for human and environmental health. Therefore, there is a need to develop ecologically safe tactics, such as the use of the entomopathogenic fungus (EPF) Metarhizium anisopliae (Metchnikoff 1879) (Met-11.1). The following study investigated the effectiveness of EPF-Met-11.1 on different demographic parameters of Ae. albopictus. Mortality bioassays showed 92.5% mortality when adult Ae. albopictus were treated with M. anisopliae. Metarhizium anisopliae absorbs the hemolymph sugar which results in retarded development. Metarhizium anisopliae LC50 not only affected the parental generation (F0) but also affected the demographic parameters of the offspring (F1). Transgenerational results (F1) with Met-11.1 showed decreased net reproductive rates (Ro), intrinsic rates of increase (r), and mean generation times (T) compared to those of uninfected controls. The larval developmental duration in the treatment group was 8.22 d, compared to 8.00 d in the control. There was a significant decrease in mean fecundity in the treated group (208.87 eggs) compared to that of the control group (360.27 eggs), and adult longevity was also significantly reduced in the treated group. Therefore, it is concluded that M. anisopliae can have lasting effects on the developmental parameters of Ae. albopictus, indicating that it can be an integral part of mosquito control strategies.

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Prevalência e riscos de diabetes e hipertensão em pacientes com dengue: uma metanálise

Silva,

Sousa,

Souza

et al. 2024

Cad. Pedagógico

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A dengue, uma doença infecciosa transmitida por mosquitos, é exacerbada por diabetes e hipertensão, aumentando a gravidade e complicações. Prevenção foca no controle de mosquitos. Estudos analisam essa relação. Foram incluídos estudos sobre a associação entre dengue, diabetes e hipertensão em adultos, focando na mortalidade. Bases de dados utilizadas: Google Scholar, ScienceDirect e MEDLINE. Dois revisores independentes realizaram triagem, extração de dados e avaliação do risco de viés usando a escala Newcastle-Ottawa. Análises estatísticas foram conduzidas com o software JASP. Após uma busca em bases de dados, 205 artigos foram inicialmente identificados. Após triagem, 35 estudos foram incluídos. Os resultados mostraram uma prevalência de diabetes de 16% e hipertensão de 22% entre pacientes com dengue. Odds ratios indicaram que diabetes e hipertensão aumentam significativamente o risco de complicações graves da dengue. A avaliação do risco de viés foi conduzida usando a escala de Newcastle-Ottawa, variando de 4 a 9 estrelas. Esses achados indicam um risco significativamente maior dessas condições entre pacientes com dengue. A heterogeneidade elevada entre os estudos reflete variações metodológicas e populacionais. É essencial monitorar essas comorbidades para melhorar os desfechos clínicos em dengue.

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Dengue: A Silent Killer, a Worldwide Threat

Cited by 3 publications

References 91 publications

Molecularly Imprinted Polymers: Promising Tool for the Human Virus Detection

Molecularly Imprinted Polymers: Promising Tool for the Human Virus Detection

Pathogenicity and Transgenerational Effects of Metarhizium anisopliae on the Demographic Parameters of Aedes albopictus (Culicidae: Diptera)

Prevalência e riscos de diabetes e hipertensão em pacientes com dengue: uma metanálise

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