Dendrophen, a Novel Glycyrrhetyl Amino Acid from Dendronephthya hemprichi

Shaaban, Mohamed; Shaaban, Khaled A.; Abd‐Alla, Howaida I.; Hanna, Atef G.; Laatsch, Hartmut

doi:10.1515/znb-2011-0413

Cited by 11 publications

(8 citation statements)

References 18 publications

(23 reference statements)

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“…As further colorless needles, compound 2 was obtained as the most predominant substance in the plant's extract with additional low polarity. The compound displayed no UV activity on TLC as well, while it was detected as pink on spraying with anisaldehyde/sulphuric acid and turned later as violet, referring most likely to a terpenoidal moiety [ 23 ]. According to the EI-MS, compound 2 exhibited a molecular ion peak at m / z 440 followed by expulsion of the methyl group to afford a fragment ion peak at m / z 425.…”

Section: Resultsmentioning

confidence: 99%

Ecological and Phytochemical Studies on Euphorbia retusa (Forssk.) from Egyptian Habitat

Shaaban

Ali

Tala

et al. 2018

Journal of Analytical Methods in Chemistry

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This study deals with the ecology, phytochemistry, and biological activity investigation of Euphorbia retusa, belonging to Euphorbiaceae family, obtained from Egypt. Ecologically, Euphorbia retusa secretes white sap inhibiting the growth of the other species, so Euphorbia retusa is forming complete patches. Phytochemical study of the plant was visualized intensively based on its extraction with a protic organic solvent, working up and purifying its entire bioactive compounds using a series of different chromatographic techniques. A broad range of diverse compounds were isolated, namely, 1-hexacosanol (1), 3β-hydroxy-24-methylene-9,19-cyclolanostane; 24-methylenecycloartanol (2), 3β-hydroxy-9,19-cyclolanostane; cyclolaudanol (3), 3β,24S-Ergost-5-en-ol (4), and methyllinoleate. Additionally, GC-MS analysis of the unpolar fractions detected the existence of n-dodecane, methyllaurate, 6,10,14-trimethyl-pentadecan-2-one (5), 6,10-dimethyl-undecan-2-one (6), 2-methyl-hexadecanal (7), methylpalmitate, methyl-9,12,15-octadecatrienoate (8), and n-heneicosane (9). A full assignment for compounds 2 and 3 using 1 and 2 DNMR was carried out herein for the first time. The antimicrobial activity of the strain extract and obtained compounds was studied using a panel of pathogenic bacterial strains. The in vitro cytotoxicity of the compounds as well as the crude extract was studied against the human cervix carcinoma cell line (KB-3-1).

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Section: Resultsmentioning

confidence: 99%

Ecological and Phytochemical Studies on Euphorbia retusa (Forssk.) from Egyptian Habitat

Shaaban

Ali

Tala

et al. 2018

Journal of Analytical Methods in Chemistry

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“…Compound 1 , a moderately polar colourless solid, appeared on TLC as an intensive pink spot that changed to violet on spraying with anisaldehyde/sulfuric acid and heating. As it did not show UV absorption or fluorescence, characteristic for conjugated systems, we supposed it to be a terpenoid [ 30 ]. The molecular formula of 1 was determined as C 26 H 38 O 7 by negative mode ESI-HR-MS ( Table 1 ), indicating the presence of eight double bond equivalents (DBE).…”

Section: Resultsmentioning

confidence: 99%

Terretonin N: A New Meroterpenoid from Nocardiopsis sp.

et al. 2018

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Terretonin N (1), a new highly oxygenated and unique tetracyclic 6-hydroxymeroterpenoid, was isolated together with seven known compounds from the ethyl acetate extract of a solid-state fermented culture of Nocardiopsis sp. Their structures were elucidated by spectroscopic analysis. The structure and absolute configuration of 1 were unambiguously determined by X-ray crystallography. The isolation and taxonomic characterization of Nocardiopsis sp. is reported. The antimicrobial activity and cytotoxicity of the strain extract and compound 1 were studied using different microorganisms and a cervix carcinoma cell line, respectively.

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“…, a new sterol, dendrotriol(71), along with the wellknown metabolites, cholesterol(26) [30] (Figure 4) and hexitol (72)[66]. The structures of new compounds 70 and 71 were established by spectroscopic methods, although the stereocehmsitry for C-24 stereogenic center in 71 was not determined[66].…”

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confidence: 99%

Natural Products from Octocorals of the Genus Dendronephthya (Family Nephtheidae)

Chen¹,

Chang

Chen

et al. 2020

Molecules

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In this review, 170 natural substances, including steroid, diterpenoid, sesquiterpenoid, peptide, prostaglandin, base, chlorolipid, bicyclolactone, amide, piperazine, polyketide, glycerol, benzoic acid, glycyrrhetyl amino acid, hexitol, pentanoic acid, aminoethyl ester, octadecanone, alkaloid, and a 53-kD allergenic component from octocorals belonging to genus Dendronephthya, were listed. Some of these compounds displayed potential bioactivities.

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Dendrophen, a Novel Glycyrrhetyl Amino Acid from Dendronephthya hemprichi

Cited by 11 publications

References 18 publications

Ecological and Phytochemical Studies on Euphorbia retusa (Forssk.) from Egyptian Habitat

Ecological and Phytochemical Studies on Euphorbia retusa (Forssk.) from Egyptian Habitat

Terretonin N: A New Meroterpenoid from Nocardiopsis sp.

Natural Products from Octocorals of the Genus Dendronephthya (Family Nephtheidae)

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