Dendrobium huoshanense C.Z.Tang et S.J.Cheng: A Review of Its Traditional Uses, Phytochemistry, and Pharmacology

Abstract

Dendrobium huoshanense, a traditional medicinal and food homologous plant, belongs to the family Orchidaceae and has a long history of medicinal use. It is reported that the stem of D. huoshanense has a variety of bioactive ingredients such as polysaccharides, flavonoids, sesquiterpenes, phenols, etc. These bioactive ingredients make D. huoshanense remarkable for its pharmacological effects on anti-tumor, immunomodulation, hepatoprotective, antioxidant, and anticataract activities. In recent years, its rich pharmacological activities have attracted extensive attention. However, there is no systematic review focusing on the chemical compositions and pharmacological effects of D. huoshanense. Therefore, the present review aims to summarize current research on the chemical compositions and pharmacological activities of D. huoshanense. This study provides valuable references and promising ideas for further investigations of D. huoshanense.

Selection of Suitable Reference Genes for Gene Expression Normalization Studies in Dendrobium huoshanense

“…D. huoshanense has attracted many researchers because of its broad pharmacological activity [ 9 ]. Our research group on D. huoshanense has carried out a series of studies on the field resource protection, tissue culture and cultivation, chemical component separation and identification, bioactivity analysis and action mechanism, and new drug and product development [ 3 , 5 , 10 , 39 , 50 , 51 , 52 , 53 ], and also completed its whole genome sequencing [ 54 ].…”

“…The major active components of D. huoshanense are polysaccharides, flavonoids, sesquiterpenes, phenols, etc. [ 3 , 7 , 8 , 9 ]. Many pharmacological experiments showed that it has the effect of enhancing immunity, anti-oxidation, anti-aging, anti-tumor, and that it plays a role in reducing blood sugar, protecting the liver, etc.…”

Dendrobium huoshanense Polysaccharide Improves High‐Fat Diet Induced Liver Injury by Regulating the Gut‐Liver Axis

“…Dendrobium huoshanense has a medicinal history over 1,000 years in China and ranks first among the “Top Ten Anhui Medicines.” It has been included in the Chinese Pharmacopoeia and also approved for use as a raw food material [27] . “Shennong's Classic of Materia Medica” lists it as the top grade, noting that it has taken a long time to thicken the intestines and stomach and replenish the deficiencies of the five internal organs [27] .…”

“…It has been included in the Chinese Pharmacopoeia and also approved for use as a raw food material. [27] "Shennong's Classic of Materia Medica" lists it as the top grade, noting that it has taken a long time to thicken the intestines and stomach and replenish the deficiencies of the five internal organs. [27] Ancient Chinese medicine books and modern research have documented the related effects of D. huoshanense with its ability to "thicken the intestines and stomach" and "nourish the liver yin."…”

“…Dendrobium huoshanense has a medicinal history over 1,000 years in China and ranks first among the “Top Ten Anhui Medicines.” It has been included in the Chinese Pharmacopoeia and also approved for use as a raw food material [27] . “Shennong's Classic of Materia Medica” lists it as the top grade, noting that it has taken a long time to thicken the intestines and stomach and replenish the deficiencies of the five internal organs [27] . Ancient Chinese medicine books and modern research have documented the related effects of D. huoshanense with its ability to “thicken the intestines and stomach” and “nourish the liver yin.” [28] D. huoshanense polysaccharide (DHP) is one of the most important active components of D. huoshanense ; it is composed of several monosaccharides, such as glucose, xylose, and galactose, and has various biological activities [28] .…”