Dendrimers: design, synthesis and chemical properties

Abstract

Dendrimers in Medicine and Biotechnology: New Molecular Tools looks at this exciting and rapidly growing area of science. Using an interdisciplinary approach with particular emphasis on biological applications, the book discusses the relationship between the dendrimer molecular motif and its biological properties.

Electrochemical impedimetry of electrodeposited poly(propylene imine) dendrimer monolayer

“…Dendrimers are synthetic three-dimensional macromolecules with a well-defined, highly branched and globular shaped molecular structure [1,2]. A notable example among the various types of dendrimers is poly(propylene imine) (PPI).…”

Specific vapor sorption properties of phosphorus-containing dendrimers

“…The selectivity of dendrimers may be high because of their ability to sorb different substrates in different binding sites. Being derived from structural considerations [5], the presence of different binding sites in dendrimers was directly proved by 1 H NMR [6] and fluorescent [7] titration in solution. For dendrimers in solid state, this feature was concluded from dependence of guest uptake on their generation number [8] and from different adsorption kinetics for different substrates [9].…”

Synthesis of thermoresponsive unimolecular polymeric micelles with a hydrophilic hyperbranched poly(glycidol) core

“…The special properties of dendritic boxes make them useful in many applications such as in drug release, molecular labels, probe moieties, chemical sensors, holographic data storage and molecular shuttles for transporting guest molecules between two different phases. [26][27][28][29][30][31][32] However, dendrimers are synthesized by complicated multistep reactions that limit their bulk applications. Hyperbranched polymers, which are the imperfect analogs of dendrimers, can be used as a potential alternative because they can be obtained conveniently in a single step and in high yield.…”