Demonstration of Re-entry within the His-Purkinje System in Man

Abstract

SUMMARYRe-entry within the His-Purkinje system (HPS) was consistently observed in 15/24 consecutive patients in whom retrograde refractory period studies were performed using His bundle electrograms and the ventricular extrastimulus method. Within a narrow range of ventricular coupling intervals (V,V2), V, retrogradely conducted to the bundle of His (H2) with significant infra-His bundle conduction delay (V2H2 interval). At critical V2H2 delays another beat of ventricular origin (V3) followed V2 and was associ…