Demographics of paediatric renal replacement therapy in Europe: 2007 annual report of the ESPN/ERA-EDTA registry

Chesnaye, Nicholas; Bonthuis, Marjolein; Schaefer, Franz; Groothoff, Jaap W.; Verrina, Enrico; Heaf, James; Jankauskienė, Augustina; Lukosiene, Viktorija; Молчанова, Е. А.; Mota, Conceição; Peco-Antić, Amira; Ratsch, Ilse Maria; Bjerre, Anna; Roussinov, Dimitar; Сукало, А. В.; Topaloğlu, Rezan; Hoeck, Koen Van; Zagożdżon, Ilona; Jager, Kitty J.; Stralen, Karlijn J. van

doi:10.1007/s00467-010-1472-7

Cited by 86 publications

(21 citation statements)

References 5 publications

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“…7,11,12 However, diabetes is an unlikely cause of end-stage renal disease in children and young adults. 3,[13][14][15] Our results suggests that the higher incidence of end-stage renal disease among young Aboriginal people is due to their higher risk of glomerulonephritis compared with young white people. Furthermore, congenital anomalies (a major cause of kidney failure in chil- Note: CI = confidence interval, OR = odds ratio.…”

Section: Discussionmentioning

confidence: 67%

Incidence and causes of end-stage renal disease among Aboriginal children and young adults

Samuel

Foster

Hemmelgarn

et al. 2012

CMAJ

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Background: Although Aboriginal adults have a higher risk of end-stage renal disease than non-Aboriginal adults, the incidence and causes of end-stage renal disease among Aboriginal children and young adults are not well described. Methods:We calculated age-and sex-specific incidences of end-stage renal disease among Aboriginal people less than 22 years of age using data from a national organ failure registry. Incidence rate ratios were used to compare rates between Aboriginal and white Canadians. To contrast causes of end-stage renal disease by ethnicity and age, we calculated the odds of congenital diseases, glomerulonephritis and diabetes for Aboriginal people and compared them with those for white people in the following age strata: 0 to less than 22 years, 22 to less than 40 years, 40 to less than 60 years and older than 60 years.Results: Incidence rate ratios of end-stage renal disease for Aboriginal children and young adults (age < 22 yr, v. white people) were 1.82 (95% confidence interval [CI] 1.40-2.38) for boys and 3.24 (95% CI 2.60-4.05) for girls. Compared with white people, congenital diseases were less common among Aboriginal people aged less than 22 years (odds ratio [OR] 0.56, 95% CI 0.36-0.86), and glomerulonephritis was more common (OR 2.18, 95% CI 1.55-3.07). An excess of glomerulonephritis, but not diabetes, was seen among Aboriginal people aged 22 to less than 40 years. The converse was true (higher risk of diabetes, lower risk of glomerulonephritis) among Aboriginal people aged 40 years and older. Interpretation:The incidence of end-stage renal disease is higher among Aboriginal children and young adults than among white children and young adults. This higher incidence may be driven by an increased risk of glomerulonephritis in this population. AbstractResearch CMAJ, October 2, 2012, 184 (14) E759

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Section: Discussionmentioning

confidence: 67%

Incidence and causes of end-stage renal disease among Aboriginal children and young adults

Samuel

Foster

Hemmelgarn

et al. 2012

CMAJ

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“…All countries collected individual patient data on date of birth, sex, treatment modality at start and changes in treatment [7]. Incident patients aged ≤17 years who started RRT between 2002 and the end of 2007 were included in the current analysis.…”

Section: Methodsmentioning

confidence: 99%

Determinants of eGFR at start of renal replacement therapy in paediatric patients

Stralen¹,

Tizard²,

Jager³

et al. 2010

Nephrology Dialysis Transplantation

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“…In 2000, the prevalence and incidence of children on renal replacement therapy (RRT) in the European Renal Association – European Dialysis and Transplant Association (ERA‐EDTA) Registry was 62.1 per million and 9.9 per million, respectively, of age‐related populations 1 . The latest data of the 2007 report from the European Society for Paediatric Nephrology/European Renal Association‐European Dialysis and Transplant Association (ESPN/ERA‐EDTA) revealed lower prevalence (33.6 per million) and incidence (6.5 per million) of age‐related populations 2 . The Australia/New Zealand (ANZDATA) Registry reported end‐stage renal disease (ESRD) occurring in about 5–10 children per million of age‐related populations each year 3 .…”

Section: Introductionmentioning

confidence: 99%

Survival analysis of pediatric dialysis patients in Taiwan

et al. 2012

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Demographics of paediatric renal replacement therapy in Europe: 2007 annual report of the ESPN/ERA-EDTA registry

Cited by 86 publications

References 5 publications

Incidence and causes of end-stage renal disease among Aboriginal children and young adults

Incidence and causes of end-stage renal disease among Aboriginal children and young adults

Determinants of eGFR at start of renal replacement therapy in paediatric patients

Survival analysis of pediatric dialysis patients in Taiwan

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