Demographic Profile of NSTEMI (Non ST Elevation Myocardial Infarction) Patients &amp; Association of ST-Segment Depression and Level of Troponin I with NSTEMI Patient's In-Hospital Outcome

Zahid, Abu; Khan, HI Lutfur Rahman; Chowdhury, Abdul Wadud; Sabah, Khandker Md Nurush; Kabir, SM Eftar Zahan; Rahman, Hafizur; Hossain, Mofazzal; Khan, Tunaggina Afrin

doi:10.3329/medtoday.v27i2.30038

Cited by 7 publications

(12 citation statements)

References 13 publications

(21 reference statements)

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“…Also, Killip classification was a powerful independent predictor of NSTE-ACS [16][17][18]. Additionally, some other studies have suggested that factors such as age, heart rate, systolic BP, ST-segment depression and cardiac enzymes as the strongest predictor of mortality and MI [19,20]. Results of these studies are in line with the current study.…”

Section: Discussionsupporting

confidence: 90%

Predictors of the extent and severity of coronary artery disease for prognosis of patients with non-ST-segment elevation acute coronary syndromes

Patel¹,

Prajapati

Patel

et al. 2018

ijcp

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Introduction: The proportion of patients visiting emergency department with chest pain indicative of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is increasing. The current risk assessment of patients with NSTE-ACS may calculate patients risk for recurrent events but may fail to identify patients with severe coronary artery disease (CAD). The present study aimed to identify predictors of the extent and severity of CAD for prognosis of NSTE-ACS patients undergoing early angiography. Methods: A total of 215 patients with NSTE-ACS were enrolled randomly and followed up between April-2015 and February-2017 at a tertiary healthcare center. The coronary angiography was performed. Patients were divided into two groups: high-risk coronary anatomy (HRCA) and low-risk coronary anatomy (LRCA). Patients were analyzed for baseline, demographic, clinical characteristics, and cardiovascular risk factors, during hospitalization and 30 days post discharge. Results: Among 215 enrolled patients, 90 (mean age: 52.22 ± 10.24 year) and 125 (mean age: 57.78 ± 8.83 year) patients were in the LRCA and HRCA group, respectively. The presence of previous heart failure [

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Section: Discussionsupporting

confidence: 90%

Predictors of the extent and severity of coronary artery disease for prognosis of patients with non-ST-segment elevation acute coronary syndromes

Patel¹,

Prajapati

Patel

et al. 2018

ijcp

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“…This study revealed that 35 (70.0%) patients of group A were smoker and 33 (66.0%) patients of group B were smoker; difference was not statistically significant (p=0.668). Zahid et al, (2015) in their study reported similar findings [21].…”

Section: Discussionsupporting

confidence: 70%

An Observational Study to Assess Outcome of NSTEMI Patients with Raised Serum Uric Acid Level in a Tertiary Care Hospital of Bangladesh

2020

COA

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Background: Non-ST segment elevation myocardial infarction (NSTEMI) is the commonest form of ACS and a leading global cause of premature morbidity and mortality. Evidences link serum uric acid with short and long-term major adverse outcomes (MACE) in patients with NSTEMI. Objective: To see in-hospital outcome of NSTEMI patients with raised serum uric acid level. Methodology: This cross-sectional observational study was conducted in the Department of Cardiology, Sylhet MAG Osmani Medical College Hospital, Sylhet during the period from July, 2017 to June, 2019. Fifty NSTEMI patients with raised serum uric acid (>7mg/dl in male; >6mg/dl in female) level (Group A) and fifty NSTEMI patients with normal serum uric acid level (group B) admitted within 24 hours of symptom onset were consequently enrolled. In-hospital complications and mortality were recorded while continuing standard treatment for the event. Results: The mean age was 60.82 (SD 9.62) years in group A and 49.90 (SD 10.40) years in group B. The mean age of the patients of group A was significantly higher than patients of Group B (p<0.001). Male preponderance was in both groups (84.0% versus 80.0%; p=0.603). Diabetes mellitus (52.0% versus 22.0%; p=0.002), hypertension (78.0% versus 52.0%; p=0.039) and dyslipidaemia (48.0% versus 12.0%; p<0.001) were more frequent in group A than that of group B. But smoking status (70.0% versus 66.0%; p=0.668), family history of CAD (10.0% versus 26.0%; p=0.476) did not differ significantly. Killip class did not differ significantly between group A and group B (p=0.127). In-hospital mortality was 5 (10.0%) patients in group A and 2 (4.0%) patients in group B; did not reach the level of significance (p>0.05) and complications such as post MI angina, cardiogenic shock, acute left ventricular failure, re-infarction, sinus tachycardia, sinus bradycardia, atrial flutter, atrial fibrillation, bundle branch block, ventricular tachycardia, ventricular fibrillation did not differ significantly between the two groups (p>0.05). Conclusion: There is no significant difference between in-hospital outcome (mortality and complications) of NSTEMI patients with raised and normal serum uric acid level.

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“…The majority of the patients of the present study were male (84.8% and 88.2% in group I and group II respectively), such male predominance was also reported by other researchers. 13 The gender disparity in the present study may be multifactorial e.g., lower prevalence of CAD in women, less health-care seeking attitude of females and relative unwillingness for invasive procedures. Regarding CAD risk factors, smoking, hypertension and family history of CAD did not differ significantly between the groups.…”

Section: Discussionmentioning

confidence: 71%

“…The mean age of patients in group I and II was 52.7±8.9 and 50.9±9.7 years respectively. In a study conducted at Dhaka Medical College by Zahid et al 13 the mean age of NSTEMI patients was 55.9±9.1 years. The majority of the patients of the present study were male (84.8% and 88.2% in group I and group II respectively), such male predominance was also reported by other researchers.…”

Section: Discussionmentioning

confidence: 99%

Serum Potassium and Angiographic Severity of Coronary Artery Disease in Non-ST Elevation Myocardial Infarction

Sultana¹,

Rahman

Karmakar

et al. 2021

Bangladesh Heart J

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Background: Non-ST elevation myocardial infarction (NSTEMI) patients like other patients with acute coronary syndrome (ACS) need assessment of severity of coronary artery disease (CAD) for prognostication and management. The available scoring systems are complex and include invasive parameters. On the other hand, potassium is a key element and its blood level has been shown to reflect health and disease of vasculature including in some ACS. Objective: The study was conducted to find out the relationship between serum potassium level and angiographic severity of CAD in NSTEMI. Method: A total of 200 cases of NSTEMI patients undergoing coronary angiography (CAG) were included. Patients getting medications that alter potassium homeostasis (e.g., diuretics, glucocorticoids, intravenous insulin), having renal impairment, haematological or liver disease, congenital or valvular heart disease, cardiomyopathy, prior percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) were excluded. Serum potassium was measured soon after admission with NSTEMI, and the patients were divided: mid to high normal (4 to 5.5 mmol/L) constituted the group I and low normal (3.5-3.9 mmol/L) constituted the group II. CAG was done during index admission, SYNTAX score calculated and compared between 2 groups. Results: High SYNTAX score was significantly more commonly found in group I than in group II (62.1% vs. 14.7%, p<0.001). Mean SYNTAX score was higher in group I than in group II (24.3±8.2 vs. 15.3±7.8, p<0.001). There was a linear relationship between serum potassium level and SYNTAX score. Mid to high normal serum potassium, hypertension and dyslipidemia were found to be significantly related to higher SYNTAX score with odds ratio being 10.44, 4.37 and 2.12 respectively. Conclusions: Within physiological limits, higher serum potassium level correlates with severe coronary artery disease in NSTEMI patients. It may be used as an additional tool in conjunction with other scoring systems to assess the severity of CAD in this subset of ACS patients. Bangladesh Heart Journal 2020; 35(2) : 128-133

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Demographic Profile of NSTEMI (Non ST Elevation Myocardial Infarction) Patients & Association of ST-Segment Depression and Level of Troponin I with NSTEMI Patient's In-Hospital Outcome

Cited by 7 publications

References 13 publications

Predictors of the extent and severity of coronary artery disease for prognosis of patients with non-ST-segment elevation acute coronary syndromes

Predictors of the extent and severity of coronary artery disease for prognosis of patients with non-ST-segment elevation acute coronary syndromes

An Observational Study to Assess Outcome of NSTEMI Patients with Raised Serum Uric Acid Level in a Tertiary Care Hospital of Bangladesh

Serum Potassium and Angiographic Severity of Coronary Artery Disease in Non-ST Elevation Myocardial Infarction

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