Demographic, emotional and social determinants of cannabis use in early pregnancy: The Generation R study

Marroun, Hanan El; Tiemeier, Henning; Jaddoe, Vincent W. V.; Hofman, Albert; Mackenbach, Johan P.; Steegers, Eric A.P.; Verhulst, Frank C.; Brink, Wim van den; Huizink, Anja C.

doi:10.1016/j.drugalcdep.2008.05.010

Cited by 97 publications

(92 citation statements)

References 35 publications

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“…Fourth, the nonresponse analysis showed small differences between women with and without urine samples, which may increase the likelihood for cannabis use in women without urine samples. However, we previously reported that paternal cannabis use is the main determinant for prenatal cannabis use [4] , and in the current study, the additional analyses showed that paternal cannabis use occurs more often when mothers report cannabis use during pregnancy or when cannabinoids are detected in urine samples. Therefore, it is essential to consider paternal cannabis use.…”

Section: Discussionmentioning

confidence: 77%

“…In pregnant women, the prevalence of cannabis use was much lower, i.e. in 2007, 2.9% of Dutch women and 1.8% of American women reported prenatal cannabis use [4,5] .…”

Section: Introductionmentioning

confidence: 99%

“…In previous studies of a population-based cohort in the Netherlands, we based prenatal cannabis use on self-reported information collected using a questionnaire in pregnancy [4,9] . Although self-report is a commonly used measure to assess substance use, it is acknowledged that individuals may underreport or deny substance use, especially during pregnancy [10] .…”

Section: Introductionmentioning

confidence: 99%

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Agreement between Maternal Cannabis Use during Pregnancy according to Self-Report and Urinalysis in a Population-Based Cohort: The Generation R Study

et al. 2010

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Aim: To verify self-reported information on prenatal drug use in urine because reporting in pregnancy is sensitive to stigma and might lead to misclassification. Methods: Using semiquantitative immunochemical analysis, the presence of the urinary metabolite (11-nor-Δ9–tetrahydrocannabinol- 9-carboxylic acid) was compared to self-reported prenatal cannabis use. Sensitivity and specificity for self-report and urinalysis outcomes were calculated and Yule’s Y was used as an agreement measure. Results: Urine samples were available for 3,997 pregnant women. Of these women, 92 reported having used cannabis during pregnancy (2.3%) and 71 had positive urine screens (1.8%). In total 35% of the 92 women with self-reported cannabis use also had a positive urine screen. Positive urines were relatively frequent in women reporting cannabis use before pregnancy only (7.6%) and in women with missing information (2.6%). Sensitivity and specificity of urinalysis compared to self-report were 0.46 and 0.98. Sensitivity and specificity of self-report compared to urinalysis were 0.36 and 0.99. Yule’s Y amounted to 0.77, indicating substantial agreement between the measures. Conclusions: Our findings illustrate the difficulties in obtaining valid information on prenatal cannabis use. To improve the quality of cannabis use data, we suggest a 2-step approach starting with self-report.

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Section: Discussionmentioning

confidence: 77%

“…In pregnant women, the prevalence of cannabis use was much lower, i.e. in 2007, 2.9% of Dutch women and 1.8% of American women reported prenatal cannabis use [4,5] .…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Agreement between Maternal Cannabis Use during Pregnancy according to Self-Report and Urinalysis in a Population-Based Cohort: The Generation R Study

et al. 2010

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“…• Les divers troubles à long terme peuvent être en lien avec d'autres facteurs de risque comme les problèmes sociaux ou environnementaux liés aux conditions de vie des femmes usagères de drogues enceintes [10,5].…”

Section: Discussionunclassified

“…• Ces troubles peuvent être induits par des psychopathologies maternelles altérant les interactions précoces mère-bébé et le développement de l'enfant [5].…”

Section: Discussionunclassified