Demographic changes in the Polish blood donors eligible for blood donation and screened for transfusion-transmitted infections (2005–2018)

Abstract

Background:The infection frequency among donors found eligible for donation (based on donor questionnaire and physical examination) and therefore the risk of post-transfusion adverse reactions has been demonstrated to be closely related to donor demographics. The aim of the study was to determine the demographic changes among Polish blood donors found eligible for donation and subjected to screening for infectious markers in the years 2005-2018. The results were referred to transfusion safety, and particularly to the risk of transfusion-transmitted infectious agents. Material and methods: Subjected to analysis were data collected i.a. to assess the epidemiology of blood-borne infectious agents: the number of screened donors found eligible for donation divided into categories by sex, first and repeat donation as well as age groups (≤ 20, 21-30, 31-40, 41-50, 51-60 and > 60 years). Frequencies (fraction) were expressed as percentage with a 95% confidence interval [95%CI] and the differences -as percentage point (p.p.). The significance of difference (p < 0.05) was verified by the Chi-squared test, and the Spearman correlation coefficient (R) was used to assess the trend.