“…Persons with special needs (PSN) are characterized by a wide spectrum of long-term physical, mental, intellectual, or sensory impairments, affecting their daily activities and influencing the provision of healthcare, including dental care [ 1 , 2 , 3 , 4 ]. In the field of special care dentistry, this group of vulnerable individuals manifests a generally higher rate of oral diseases, such as caries and periodontal diseases, and often reveals substantial additional needs of extensive, multidisciplinary, and complex dental treatment [ 5 , 6 ]. In a considerable proportion of PSN, a ‘gentle approach’, behavioral management, and/or cognitive behavioral therapy is deemed ineffective, and such patients require pharmacological management in the form of conscious sedation utilizing several pathways, as well as dental general anesthesia (GA) in the most severe cases [ 7 , 8 , 9 , 10 ].…”