Demographic and Comorbidity Pattern of Patients with Critical Limb Ischemia

Abstract

Aim: The present study aimed at identifying the pattern of patients with critical limb ischemia (CLI) compared with those with peripheral arterial occlusive disease (PAOD). Materials and methods: A four-year retrospective study was conducted with patients hospitalized in the Second Surgical Clinic at the Emergency County Hospital Cluj-Napoca. The medical charts of patients with PAOD (n=466) and CLI (n=223) were reviewed and data were collected. Results: The study included 689 patients; mean age 67 years for PAOD patients and 65 years for CLI patients. A significantly higher percentage of patients were male in both groups (79.25%, P < 0.0001). Most of the patients in both groups had received at least a secondary education (P < 0.0001). Most of the subjects in both groups were smokers (>71.30%) with no difference between groups (P = 0.566). No significant differences were found between the groups in comorbidities (diabetes, arterial blood hypertension, cardiac ischemia, rhythm disorders, P > 0.05). There were more CLI patients that were overweight than overweight patients with PAOD (P = 0.0004). High serum cholesterol (>200 mg/dL) and triglycerides (>150 mg/dL) levels were found in the CLI group (P < 0.05). Age was identified as a risk factors for amputation (OR = 1.03, 95%Cl [1.01−1.05], P = 0.0012). Conclusions: The profile of a patient with critical limb ischemia and peripheral arterial occlusive disease is a 65-67-year-old male smoker with at least a secondary education. The CLI patient is overweight with pathological serum levels of cholesterol and triglycerides.

Time trends in the risk of atrial fibrillation and ischaemic stroke in patients with peripheral artery disease between 1997 and 2015

“…PAD is considered as a serious atherosclerosis-related disease that can lead to frequent hospitalisations, higher health economic cost, a poor quality of life and an increased mortality rate. [14][15][16] Although PAD definition is that of atherosclerosis of the arteries outside the heart, the term is most commonly used to describe occlusive arterial disease of the lower extremities. 17 Similar to other atherosclerotic diseases, PAD is associated with the presence of traditional cardiovascular risk factors, including DM, hypertension, dyslipidaemia, obesity and tobacco consumption.…”

Use of intravenous alprostadil in patients with severe critical ischemia of the lower limbs

“…11 The mean age of the patients evaluated was similar to that reported in studies by Peña-Corte´s et al, Karles-Ernotte et al, and Lawell et al, which had similar populations (72 to 74.5 years); however, these studies had a greater proportion of men, which did not occur in our series of cases, which had a symmetric distribution in both sexes. 9,[12][13][14][15] The discrepancy in results may be related to the high cardiovascular risk and increased peripheral arterial damage in the elderly female population of Colombia.…”

Education Level Among Patients with Major Limb Amputation

“…Goodney et al reported an amputation rate of more than 23 per 10,000 Medicare patients with the peripheral arterial disease (PAD) in Florence, South Carolina [6]. Certain factors, such as age, gender, race, co-existing diseases, smoking, and socioeconomic status, among others, have been associated with higher rates of amputation [6,[8][9][10][11][12]. For example, Ciocan et al identified age as a risk factor for amputation [8].…”

“…Certain factors, such as age, gender, race, co-existing diseases, smoking, and socioeconomic status, among others, have been associated with higher rates of amputation [6,[8][9][10][11][12]. For example, Ciocan et al identified age as a risk factor for amputation [8]. Arya et al found the race to be independently predictive of major limb amputation in patients with PAD [11].…”