Demographic and Clinical profile of 190 COVID-19 Patients in a Tertiary Care Private Hospital of Dhaka, Bangladesh: An Observational Study

Hossain, Homayara Tahseen; Chowdhury, Tasmina; Majumder, Maksudul Islam; Ava, Arfa Rahman; Rahman, Quazi Audry Arafat; Zahiruddin,; Ahasan, Ham Nazmul; Islam, Quazi Tarikul

doi:10.3329/jom.v21i2.50210

Cited by 10 publications

(23 citation statements)

References 10 publications

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“…Other observational studies of Bangladesh 22,23,24 , and china 7,14 support similar findings. In our study, mild category patients present with a lower percentage of co-morbid conditions than moderate to critical ones.…”

Section: Discussionsupporting

confidence: 59%

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Comprehensive Overview of 473 Cases of COVID-19: Outcome Experiences of a Dedicated Hospital in Dhaka, Bangladesh

Ra¹,

Nasir²,

Ferdous³

et al. 2021

GJMR

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Aim: The study aimed to observe and compare the demographic, comorbidities, biomarkers in different categories of diagnosed COVID-19 patients admitted to a COVID dedicated tertiary care hospital in the pic time of the pandemic, 2020, at Dhaka, Bangladesh. Methods: This retrospective study was conducted from May to September 2020 in 720 bed Holy Family Red Crescent Medical College Hospital. Four hundred seventy-three patients included in this study, diagnosed by RT-PCR of the nasopharyngeal swab, were divided into four groups. The mild group includes 254 patients, the moderate group has 82 patients, 38 patents in the severe group, and the critical group who were admitted to ICU, 99 patients. Demographic data, available investigation reports of individual patients, obtained from hospital records manually and compared between all four different categories of patients.

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Section: Discussionsupporting

confidence: 59%

“…Anosmia was absent in the critical group. Several studies in Bangladesh 19,20,22,23 and worldwide 7,14 show patients with similar symptoms.…”

Section: Discussionmentioning

confidence: 83%

Comprehensive Overview of 473 Cases of COVID-19: Outcome Experiences of a Dedicated Hospital in Dhaka, Bangladesh

Ra¹,

Nasir²,

Ferdous³

et al. 2021

GJMR

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“…However, almost two-thirds of the patients in ICU having CKD were deceased in our study cohort whereas DM and HTN were the most common comorbidities in both survivors and a deceased group of patients. A similar finding was observed in other studies conducted in hospitals in Dhaka, Bangladesh 22,23 . Whereas, pre-existing COPD and ischemic heart diseases were reported as more common comorbidities among critically ill COVID-19 patients in ICU of the UK, USA, and Italy.…”

Section: Discussionsupporting

confidence: 91%

“…Moreover, demographic and epidemiological characteristics of critically ill patients played a vital role in the duration of stay in ICU, like age or related comorbidities. As this is a novel coronavirus, the length of stay in ICU ranges between ages; even between survivor or non-survivor [10][11][12] .…”

Section: Paradox Of Predictors In Critically Ill Covid-19 Patients: Outcome Of a Covid-dedicatedmentioning

confidence: 99%

Paradox of Predictors in Critically ill COVID-19 Patients: Outcome of a COVID-dedicated Intensive Care Unit

Nasir¹,

Perveen²,

Nazneen

et al. 2021

Preprint

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Background: The study aimed to analyze the demographic, comorbidities, biomarkers, pharmacotherapy, and ICU-stay with the mortality outcome of COVID-19 patients admitted in the intensive care unit of a tertiary care hospital in a low-middle income country, Bangladesh. Methods: The retrospective cohort study was done in Holy Family Red Crescent Medical College Hospital from May to September 2020. All 112 patients who were admitted to ICU as COVID-19 cases (confirmed by RT-PCR of the nasopharyngeal swab) were included in the study. Demographic data, laboratory reports of predictive biomarkers, treatment schedule, and duration of ICU-stay of 99 patients were available and obtained from hospital records (non-electronic) and treatment sheets, and compared between the survived and deceased patients. Results: Out of 99 patients admitted in ICU with COVID-19, 72 were male and 27 were female. The mean age was 61.08 years. Most of the ICU patients were in the 60 - 69 years of age group and the highest mortality rates (35.89%) were observed in this age range. Diabetes mellitus and hypertension were the predominant comorbidities in the deceased group of patients. A significant difference was observed in neutrophil count, creatinine and, NLR, d-NLR levels that raised in deceased patients. There was no significant difference as a survival outcome of antiviral drugs remdesivir or favipiravir, while the use of cephalosporin was found much higher in the survived group than the deceased group (46.66% vs 20.51%) in ICU. Conclusions: Susceptibility to developing critical illness due to COVID-19 was found more in comorbid males aged more than 60 years. There were wide variations of the biomarkers in critical COVID-19 patients in a different population, which put the healthcare workers into far more challenge to minimize the mortality in ICU in Bangladesh and around the globe during the peak of the pandemic.

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“…16,25,26 Almost 18.5% cases suffered from anorexia in the present study; and more in the 30-39-years age group; several studies show similar results. 24,26 Among 254 patients, diabetes and hypertension were more predominant in the 40-49-years age, may be because these diseases are frequent in the middle-aged population. IHD was more in >60-years age group, as increased age predispose to IHD.…”

Section: Discussionsupporting

confidence: 82%

Overview of 254 mild cases of COVID-19 in Bangladeshi cohort: a cross-sectional observation

Zahan¹,

Nasir²,

Perveen³

et al. 2021

Int J Adv Med

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Background: The first recognition of a cluster of COVID-19 patients in China in late 2019, has become a major concern due to its greater transmissibility and vulnerability of the patient to turn to fever, cough, breathlessness, pneumonia then eventually severe acute respiratory distress syndrome requiring intensive care unit (ICU) support. But most of the affected patients get cured following mild symptoms and very only a few of them get hospitalized. The objective of the study was to observe the demographic characteristics, clinical symptoms, comorbidities, and biomarkers (hematological, inflammatory, hepatic, renal, and metabolic) of mild cases of COVID-19 infected patients admitted to the hospital during the peak four months of the pandemic.Methods: Age, sex, symptoms, comorbidities, and biomarkers (Hb%, WBC, lymphocyte, neutrophil, platelet count, HCT(hematocrit), NLR(neutrophil-lymphocyte ratio, d-NLR derived neutrophil-lymphocyte ratio, PLR(platelet-lymphocyte-ratio), d-Dimer, ferritin, CRP(C-reactive protein), PT(prothrombin time), INR(international normalized ratio), SGPT, S.creatinine, HbA1C of all rt-PCR positive mild cases were recorded in this retrospective observational study in a tertiary care hospital dedicated to COVID-19 at Dhaka, Bangladesh was done from 15th May to 9th September, 2020. Age, sex, symptoms, and comorbidities were compared by chi-square test and biomarkers were compared by one-way ANOVA. Results: Out of 254 cases 44 were female and 210 were male with a ratio of 1:4.77. Average age was 39.04. Largest population belongs to the 30-39 years of age range. Among the symptoms, anorexia (18.5%), fever (17.71%), and anosmia (16.9%) were most prevalent symptoms among the mild cases. However, diabetes mellitus (DM) and hypertension (HTN) were predominant comorbidities. Mostly all the biomarkers were significant among groups (Hb%, Total WBC, neutrophil count, platelet count, HCT, NLR, d-NLR, d-Dimer, ferritin, CRP, PT, SGPT, creatinine, HbA1C except lymphocyte count, PLR, and INR. The severity of disease progression depends on the co-morbidity and hyper-responsiveness inflammatory or immunological biomarkers to predict.Conclusions: In mild cases of COVID-19 male predominance was more and the most affected group was 30-39 years. They suffered more from anorexia and fever and DM and HTN were common comorbidities. Mostly all the biomarkers were significant. Moreover, further large-scale studies are needed to evaluate the number of mild cases and their prognostic features to develop and modify the treatment strategy and public health awareness time to time.

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Demographic and Clinical profile of 190 COVID-19 Patients in a Tertiary Care Private Hospital of Dhaka, Bangladesh: An Observational Study

Cited by 10 publications

References 10 publications

Comprehensive Overview of 473 Cases of COVID-19: Outcome Experiences of a Dedicated Hospital in Dhaka, Bangladesh

Comprehensive Overview of 473 Cases of COVID-19: Outcome Experiences of a Dedicated Hospital in Dhaka, Bangladesh

Paradox of Predictors in Critically ill COVID-19 Patients: Outcome of a COVID-dedicated Intensive Care Unit

Overview of 254 mild cases of COVID-19 in Bangladeshi cohort: a cross-sectional observation

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