Demodex Folliculitis Presenting as Periocular Vesiculopustular Rash

Yun, Samuel; Levin, Flora; Servat, Juan Javier

doi:10.3109/01676830.2013.812124

Cited by 12 publications

(14 citation statements)

References 6 publications

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“…A study of 48 patients with rosacea revealed 5.7 times higher density of D. folliculorum colonization compared to healthy controls, indicating an association between the two conditions (Casas et al, ). However, causation has yet to be established (Bachmeyer & Moreno‐Sabater, ; Chen & Plewig, ; Cotliar & Frankfurt, ; Elston & Elston, ; Sabater‐Marco, Escutia‐Munoz, & Botella‐Estrada, ; Vu & English III, ; Yun, Levin, & Servat, ).…”

Section: Introductionmentioning

confidence: 99%

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Treatment of Demodex ‐associated inflammatory skin conditions: A systematic review

Jacob

VanDaele

Brown

2019

Dermatologic Therapy

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Bacterial folliculitis, rosacea, and other common skin conditions have been linked to infestation by Demodex mites (human demodicosis). Currently, there is little guidance for treatment of inflammatory conditions associated with demodicosis. Thus, the objective of this review is to evaluate the efficacy and safety of treatments utilized for Demodex infestation. PubMed (1946 to January 2019) and Embase (1947 to January 2019) were searched with the following term combinations: Demodex mites, Demodex folliculitis, demodicosis, Demodex folliculorum, or Demodex brevis and articles evaluating treatment of body surface colonization with Demodex mites were included. Common interventions used for Demodex infestation include metronidazole‐based therapies, permethrin, benzoyl benzoate, crotamiton, lindane, and sulfur. Short courses of metronidazole taken orally have shown efficacy in reducing Demodex density. Additionally, topical administration of permethrin daily or twice daily was shown to be efficacious across multiple studies. Crotamiton and benzyl benzoate were also efficacious treatments. Several therapies were associated with mild‐to‐moderate skin irritation. Due to limited data, no standard of care can be identified at this time. Efficacious treatment options may include permethrin, crotamiton, benzyl benzoate, and oral metronidazole; however, long‐term efficacy has not been established.

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Section: Introductionmentioning

confidence: 99%

“…However, causation has yet to be established (Bachmeyer & Moreno-Sabater, 2017;Chen & Plewig, 2014;Cotliar & Frankfurt, 2013;Elston & Elston, 2014;Sabater-Marco, Escutia-Munoz, & Botella-Estrada, 2015;Vu & English III, 2011;Yun, Levin, & Servat, 2013).…”

mentioning

confidence: 99%

Treatment of Demodex ‐associated inflammatory skin conditions: A systematic review

Jacob

VanDaele

Brown

2019

Dermatologic Therapy

View full text Add to dashboard Cite

show abstract

“…Demodicosis, or infection with the human Demodex mites, Demodex folliculorum and Demodex brevis, predominated the infectious blepharitis literature in 2013 [13][14][15][16][17][18][19][20][21]. Ocular adnexal manifestations of these microscopic arachnids range from asymptomatic colonization to chronic blepharitis, chalazia, madarosis, or less commonly keratoconjunctivitis and can be confused with other inflammatory dermatoses, such as folliculitis, rosacea, and dermatitis and may even mimic malignancy [12][13][14].…”

mentioning

confidence: 99%

“…Ocular adnexal manifestations of these microscopic arachnids range from asymptomatic colonization to chronic blepharitis, chalazia, madarosis, or less commonly keratoconjunctivitis and can be confused with other inflammatory dermatoses, such as folliculitis, rosacea, and dermatitis and may even mimic malignancy [12][13][14]. Demodex could also be considered in the differential diagnosis of herpetic blepharitis as Yun et al reported a case of periocular Demodex folliculitis presenting as a vesiculopustular rash [15].…”

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confidence: 99%