Demodectic Mange Associated With Lymphoma in a Ferret

Localized demodicosis due to Demodex cati on the muzzle of two cats treated with inhalant glucocorticoids

“…1 Demodicosis due to D. cati is often associated with concurrent systemic disease, including feline immunodeficiency virus infection, [2][3][4] Mycoplasma haemofelis infection, 5 hyperadrenocorticism and diabetes mellitus. 6,7 Although malnutrition, systemic illness, stress or neoplasia with associated generalized immunosuppression are commonly discussed factors linked to the development of demodicosis in several species [8][9][10][11][12][13][14][15] , local immunosuppression at the skin level appears to play an important role as well. Indeed, local immunosuppression due to the application of topical immunomodulatory drugs, such as glucocorticoids and tacrolimus, or by tumour cells has been suggested as a potential trigger for development of a localized demodicosis in humans and animals.…”

Demodicosis in a ferret caused by Demodex canis

“…Demodicosis is a common skin disease of young and immunosuppressed adult dogs. Demodicosis is rare in ferrets; it has been previously reported in two ferrets receiving topical otic glucocorticoids, one ferret with lymphoma and three geriatric ferrets with chronic otitis …”

“…Demodicosis is rare in ferrets; it has been previously reported in two ferrets receiving topical otic glucocorticoids, one ferret with lymphoma and three geriatric ferrets with chronic otitis. [1][2][3] A 7-year-old, spayed female ferret was presented for evaluation of alopecia and erythema of the periocular skin and forefeet. The ferret was receiving prednisolone 1 mg/kg orally twice daily and diazoxide 15 mg/kg orally twice daily for insulinoma.…”