Demodectic Eruptions (Demodicidosis) in the Human

Infectious agents in the pathogenesis of rosacea

“…Odkryty został w 1841 roku przez Jakuba Henlego, a jego rolę w etiopatogenezie AR opisano już w 1961 roku [18,19]. To organizm saprofityczny skóry, a jego nosicielstwo występuje u 100% populacji [20].…”

Cloning and sequence analysis of chitin synthase gene fragments of Demodex mites

“…Up to now, 140 species or subspecies have been identified, infesting the hair follicles, sebaceous glands, meibomian glands, and internal organs of 11 orders of mammals such as human, dog, sheep, cat, pig, and (Izdebska, 2010;Mederle et al, 2010), goat demodicidosis (Smith, 1961;Xu et al, 2009), livestock demodicidosis (Chakrabarti and Pradhan, 1985), and human demodicidosis (Ayres and Anderson, 1932;Ayres and Ayres, 1961;Forton and Seys, 1993;Forton et al, 2005;Zhao et al, 2010;2011a;2011c;2012c). However, the pathogenesis of demodicidosis is still uncertain, and there are no effective prevention measures.…”

Scalp folliculitis with Demodex: innocent observer or pathogen?

“…Nevertheless, some studies have demonstrated an association between Demodex and follicular inflammation [22]. This is also supported by the fact that the symptoms are clearly reduced when this parasite is correctly treated [8][9][10]14,17,[23][24][25][26][27]. On the other hand, some symptoms persist when only antibacterial therapeutic agents are used [14].…”

“…Nevertheless, D. folliculorum has also been associated with varied cutaneous pathologies [8], such as rosacea [1,[9][10][11][12][13][14], granulomatous peri-oral dermatitis [15], blepharytis [1,16,17], inflammatory nodules [1], and pustular folliculitis [8,9,18,19].…”

“…There has been some speculation about the clinical differences between the two types of rosacea [10,29]; on one hand, the one which is associated with Demodex as a causal agent presents a "dry" eruption [10], with follicular scaling, vesicles and pustules. On the other hand, the common rosacea usually presents an oily skin, without scales, and the pustules and papules appear inflamed [28].…”